Dr. Rhonda Patrick explains why visceral fat can affect metabolic health even in people who appear lean. ... cancer metabolism insulin resistance inflammation visceral fat
Watch nowLong periods of sitting are linked to poorer metabolic and cardiovascular health, yet many people struggle to fit structured exercise into busy days. A new pilot study tested whether exercise snacks, brief structured activity bouts, could improve fitness and cardiometabolic markers in sedentary women. Twenty-two healthy women aged 18 to 45 took part in the study, including 11 sedentary women and 11 physically active women who served as a reference group. Only the sedentary women completed a supervised daily exercise circuit for eight weeks, with each session lasting less than 12 minutes and c... autophagy cardiovascular exercise exercise snacks heart disease immune system insulin insulin resistance metabolism mitochondria muscle
Read moreDr. Rhonda Patrick's testimony before the United States Senate Special Committee on Aging. ... nutrition exercise obesity aging muscle policy ultra-processed foods
Watch nowIntense aerobic exercise reduces the risk of metastatic cancer by as much as 73 percent, a recent study has found. It does this by reducing the glucose consumption of the body's internal organs, effectively diverting energy away from the tumor. Researchers quantified the proteins present in the internal organs of mice and the plasma of humans and found that exercise alters multiple aspects of metabolism, including glucose uptake, mitochondrial activity, and carbohydrate utilization. Then they analyzed data from a long-term study of more than 2,700 adults living in Israel. They found that hig... exercise cancer
Read moreStress ages the immune system. Psychosocial stress, such as that experienced with discrimination or trauma, has profound effects on the human body. For example, evidence suggests that stress alters the immune system, driving inflammatory processes and impairing antiviral responses (https://pubmed.ncbi.nlm.nih.gov/21928900/). Findings from a recent study demonstrate that stress accelerates immune aging. Immune function wanes as the body ages, a phenomenon referred to as immunosenescence. This gradual deterioration of the immune system is widely considered the primary driver of the increased r... aging immune system stress
Read moreExercise elicits a wide range of physiological changes in the body that improve multiple aspects of cardiovascular, neurological, and metabolic health. The molecular mechanisms that drive these improvements are not well understood. Findings from a new study suggest that an acute bout of aerobic exercise alters more than 9,000 distinct molecules in the human body to positively influence health. The study involved 36 adults between the ages of 40 and 75 years. The average body mass index among the participants was 28, which is considered overweight. Their steady-state blood glucose levels range... exercise insulin resistance inflammation
Read moreSeveral studies have established causation showing that sleep duration is a major determinant of insulin sensitivity. ... sleep exercise obesity metabolism diabetes insulin resistance
Watch nowRhonda explains chronic stress's impact on brain, gut, immune system, and aging. Meditation buffers and improves cognitive and biological aging. ... meditation brain aging telomeres depression stress mental health
Listen nowFrom the article: > BHB is a metabolite produced by the body in response to fasting, high-intensity exercise, caloric restriction, or consumption of the low-carbohydrate ketogenic diet. Dixit said it is well known that fasting and calorie restriction reduces inflammation in the body, but it was unclear how immune cells adapt to reduced availability of glucose and if they can respond to metabolites produced from fat oxidation. > Working with mice and human immune cells, Dixit and colleagues focused on how macrophages -- specialized immune cells that produce inflammation -- respond when ex... exercise diet ketosis inflammation fasting immune system nlrp3 ketogenic diet
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