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    <a data-turbo="false" href="/episodes/how-exercise-and-sleep-support-immune-function-with-age">
      <h3 class="bold">
        [Podcast] How Exercise and Sleep Support Immune Function With Age
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      Dr. Rhonda Patrick reviews how exercise, sleep, stress management, diet, and key nutrients can support immune function with age.
...
          <span class="search-tag">nutrition</span>
          <span class="search-tag">exercise</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">sleep</span>
          <span class="search-tag">immune system</span>
          <span class="search-tag">stress</span>
          <span class="search-tag">rhonda</span>
          <span class="search-tag">heat stress</span>
          <span class="search-tag">cold stress</span>
          <span class="search-tag">supplements</span>
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        [Podcast] Aliquot #111: Why ultra-processed foods and their additives are harmful
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      Processed foods fall on a spectrum, from minimally processed (like oatmeal or canned tomatoes) to ultra-processed...
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          <span class="search-tag">aliquot</span>
          <span class="search-tag">nutrition</span>
          <span class="search-tag">diet</span>
          <span class="search-tag">ultra-processed foods</span>
          <span class="search-tag">pollution</span>
          <span class="search-tag">PFAS</span>
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        [Topic] Red light therapy (photobiomodulation)
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      [toc position=&#39;left&#39;]
Introduction
Light has profound and diverse effects on the human body, influencing sleep-wake cycles, circadian rhythmicity, mood, and immune function. In recent decades, scientists have begun exploiting the body&#39;s responses to light with photobiomodulation, a non-invasive, light-based therapeutic technique. Photobiomodulation employs specific wavelengths of light (measured in nanometers, nm) to stimulate biological processes within cells and tissues, triggering a cascade of physiological responses. A growing body of evidence suggests that photobiomodulation has potential...
          <span class="search-tag">bone</span>
          <span class="search-tag">skin</span>
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          <span class="search-tag">depression</span>
          <span class="search-tag">arthritis</span>
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        [Story] Could the cure to alcoholism be a liver hormone modulated by aerobic exercise? FGF21 changes behavior of monkeys, reducing alcohol consumption by 50%
      </h3>
</a>    <p>
      Liver-derived hormone FGF21 dramatically reduces appetite for alcohol
Researchers believe that humans first encountered alcohol long before we learnt how to control the process and make it ourselves – through the consumption of fermented fruit (https://www.jstor.org/stable/2664497?seq=1#page_scan_tab_contents). One plausible result of this long history of alcohol exposure is that we have evolved a suite of biological mechanisms for detoxifying and regulating our appetite for alcohol, which may be useful for developing new treatments for alcohol use disorder. Now, a recent randomized controlled...
          <span class="search-tag">exercise</span>
          <span class="search-tag">alcohol</span>
          <span class="search-tag">aerobic</span>
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        [Topic] Cold exposure
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      [toc position=&#39;left&#39;]
Introduction
[tweetbox text=&#39;&quot;The beneficial effects of cold exposure may be due to hormesis, a favorable biological response to a mild stressor.&quot;&#39; tweet=&#39;&quot;The beneficial effects of cold exposure may be due to hormesis, a favorable biological response to a mild stressor.&quot; https://www.foundmyfitness.com/topics/cold-exposure-therapy&#39;]
Cold exposure to promote good health is an ancient practice, now used to reduce muscle soreness and promote muscle recovery after physical activity. However, regular cold exposure may also improve glucose and lipid metabolism, decrease inflamm...
          <span class="search-tag">performance</span>
          <span class="search-tag">cholesterol</span>
          <span class="search-tag">immune system</span>
          <span class="search-tag">thermogenesis</span>
          <span class="search-tag">cold stress</span>
          <span class="search-tag">brain</span>
          <span class="search-tag">heart disease</span>
          <span class="search-tag">diabetes</span>
          <span class="search-tag">insulin resistance</span>
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          <span class="search-tag">mitochondria</span>
          <span class="search-tag">neuron</span>
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          <span class="search-tag">interesting</span>
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        [Podcast] Dr. Satchin Panda on Practical Implementation of Time-Restricted Eating &amp; Shift Work Strategies
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      Dr. Satchin Panda discusses the practical aspects of implementing fasting, time-restricted eating, shift work strategies, and more.
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          <span class="search-tag">fasting</span>
          <span class="search-tag">cancer</span>
          <span class="search-tag">obesity</span>
          <span class="search-tag">metabolism</span>
          <span class="search-tag">diabetes</span>
          <span class="search-tag">circadian rhythm</span>
          <span class="search-tag">melatonin</span>
          <span class="search-tag">time-restricted eating</span>
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        [Podcast] Dr. Guido Kroemer on Autophagy, Caloric Restriction Mimetics, Fasting &amp; Protein Acetylation 
      </h3>
</a>    <p>
      Dr. Guido Kroemer discusses immunology, cancer biology, calorie-restriction mimetics, aging, and autophagy.
...
          <span class="search-tag">aging</span>
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          <span class="search-tag">triglycerides</span>
          <span class="search-tag">fatty liver</span>
          <span class="search-tag">time-restricted eating</span>
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        [Story] Dr. Guido Kroemer on Autophagy, Caloric Restriction Mimetics, Fasting &amp; Protein Acetylation
      </h3>
</a>    <p>
      TIMELINE:
00:03:22 (https://www.youtube.com/watch?v=Gm626MgpveI&amp;amp;t=00h03m22s) - How genetically inhibiting autophagy actually increases cellular sensitivity to death and how this was counterintuitive because autophagy was thought, at one time, as a type of activity predominantly concerned with actually initiating cell death.
00:04:44 (https://www.youtube.com/watch?v=Gm626MgpveI&amp;amp;t=00h04m44s) - The external signals causing autophagy.
00:05:29 (https://www.youtube.com/watch?v=Gm626MgpveI&amp;amp;t=00h05m29s) - The role of growth factors in transporting nutrients from the outside world into the...
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