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        [Podcast] The Science of Blueberries for Brain and Vascular Health
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      Dr. Rhonda Patrick examines how one cup of blueberries daily may support vascular function, cognitive aging, metabolic health, and the gut microbiome.
...
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        [Topic] Magnesium
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Introduction
Magnesium is an essential dietary mineral. It plays critical roles in myriad physiological processes, serving as a cofactor to more than 300 enzymes in the human body and maintaining the integrity of cellular structures and DNA. Magnesium deficiency is widespread, affecting more than half of people in the U.S. and increasing the risk of many chronic conditions, including cancer, metabolic disorders, and neurodegenerative diseases.  
At a glance, magnesium participates in: 
Enzymatic reactions, serving as a cofactor for more than 300 enzymes involved in variou...
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        [Podcast] Dr. Mark Mattson on the Benefits of Stress, Metabolic Switching, Fasting, and Hormesis
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      Dr. Mark Mattson discusses how stress is essential to human survival and how exercise and intermittent fasting induce stress to promote health. 
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        [Topic] Hydrolyzed collagen 
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Background
Collagens are major structural proteins in numerous body tissues, including tendons, ligaments, cartilage, skin, blood vessels, muscles, gut tissue, and dentin.[ref doi=&#39;10.1101/cshperspect.a004978&#39;] They are the most abundant proteins in the body, comprising 30 percent of the total protein mass. The human body continuously manufactures collagens to maintain tissue structural integrity. However, aging drives a progressive decrease in protein synthesis and reduced capacity to produce new collagen.[ref doi=&#39;10.1016/S0047-6374(01)00337-2&#39;]
Collagens are also highl...
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        [Topic] Quercetin
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Background
Quercetin is a bioactive compound that exerts antioxidant and anti-inflammatory properties.[ref pmid=&#39;26393898&#39;] Research indicates that quercetin may alleviate chronic health conditions such as hypertension, neurodegenerative disease, arthritis, and lung and kidney diseases and may be beneficial in combating aging-related diseases. Although much of the quercetin research has been performed in animals, some clinical trials have been conducted, and others are ongoing. 
A naturally occurring member of the flavonoid class of plant polyphenol (https://www.foundmyfi...
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        [Topic] Zinc
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Background
Zinc is an essential nutrient that participates in numerous biological processes and modulates the activity of more than 300 enzymes and 2,000 transcription factors.[ref doi=&#39;10.1136/bmj.326.7386.409&#39;] First identified for its influence on growth and development, zinc is now understood to play critical roles in immune function, protein synthesis, wound healing, DNA synthesis, and cell division. 
History
The importance of zinc in the human diet first became apparent in the early 1960s, after a patient with a rare syndrome presented to Dr. Ananda Prasad, a physic...
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        [Topic] Vitamin C
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Background
Vitamin C, also known as ascorbic acid, is an essential nutrient, widely recognized for its antioxidant properties. These properties arise from its potent redox potential due to its capacity to donate electrons to oxidized molecules. Even in small quantities vitamin C can protect critical molecules in the body such as proteins, lipids, carbohydrates, and nucleic acids (DNA and RNA) from damage by reactive oxygen species, which are generated during normal metabolism, by active immune cells, and through exposure to toxins and pollutants (e.g., certain chemotherap...
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        [Topic] Creatine
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Creatine is a naturally occurring compound that is critical in storing and releasing cellular energy. It also participates in many biological processes driving pregnancy outcomes, maintaining bone mineral density and muscle mass in older adults, improving neurological function, and aiding the immune system to fight cancer. Creatine is best known for its widespread use as a dietary supplement to enhance physical performance. 
Creatine uptake, synthesis, storage, and supplementation
Creatine uptake
Creatine can be supplied exogenously (from dietary or supplemental sources) ...
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        [Topic] Nicotinamide mononucleotide
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Nicotinamide mononucleotide (NMN) is a precursor molecule for the biosynthesis of nicotinamide adenine dinucleotide, or NAD+, a coenzyme that participates in the production of cellular energy and DNA repair. NAD+ can also be synthesized from other precursors including nicotinamide (NAM, also called niacinamide), nicotinic acid (NA), and nicotinamide riboside (NR), which are often collectively referred to as niacin (vitamin B3) or niacin equivalents.[ref doi=&#39;10.12688/f1000research.12120.1&#39;] These precursors are not equally allocated throughout the body; rather, they exhib...
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        [Topic] Resveratrol
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Resveratrol is a natural compound found primarily in the skin of red grapes and the root of Polygonum cuspidatum (also known as Japanese knotweed). It is also present to a lesser degree in peanuts and blueberries. Resveratrol protects the plants in which it is present from fungal attack and the damaging effects of ultraviolet radiation. 
Originally extracted in the 1940s, resveratrol attracted little interest in terms of human health until 1992 when research suggested that it could mediate some of the cardioprotective effects of red wine.[ref doi=&#39;10.3390/molecules220202...
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