Hemodialysis, a blood-filtering therapy for patients with kidney failure, saves lives, yet cardiovascular disease remains the dominant cause of death in this group. With few proven preventive options, researchers tested whether high-dose omega-3 supplementation could reduce major heart and vascular events in dialysis care. In a randomized controlled trial across 26 centers in Canada and Australia, 1,228 adults receiving maintenance hemodialysis took either four fish-oil capsules daily (4 g/day of omega-3 fatty acids, including 1.6 g of EPA and 0.8 g of DHA) or a corn-oil placebo and were foll... cardiovascular omega-3
Read moreIn this clip, Dr. Rhonda Patrick explains how omega-3s impact longevity, muscle preservation, deficiency risks, and the optimal intake... ... omega-3
Watch nowAutoimmune diseases occur when the body mistakenly attacks its own tissues, driving chronic inflammation and tissue damage. However, evidence suggests that omega-3 fatty acids may benefit people with autoimmune diseases. A recent study found that omega-3s help reduce disease severity in rheumatoid arthritis and lupus but are less effective against other autoimmune disorders. Researchers conducted an umbrella review to summarize findings from 21 systematic reviews and meta-analyses on the effects of omega-3s on autoimmune diseases. They also used Mendelian randomization—a method that leverages... omega-3 inflammation genetics arthritis autoimmunity
Read moreOmega-3 fatty acids play critical roles in maintaining brain health and function, potentially reducing the risk of developing Alzheimer's disease. People who carry the APOE4 gene variant and those with obesity have a higher risk of developing the disease, suggesting that differences in metabolism could be a factor. A 2022 study found that obesity influenced the amount of omega-3 in plasma phospholipid form that is important for brain transport. Fifty people (half of whom carried the APOE4 gene) took 2.5 grams of combined docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) daily for six ... brain alzheimer's obesity omega-3 genetics dementia
Read moreFlaxseed oil is rich in alpha-linolenic acid (ALA), a precursor to docosahexaenoic acid (DHA), an omega-3 fatty acid critical for infant brain and eye development. A recent study found that supplementing the diets of lactating women with flaxseed oil altered the levels of some omega-3 fatty acids in breast milk, plasma, and red blood cells but not DHA. The study involved seven lactating women who consumed 20 grams of flaxseed oil daily for four weeks. Researchers collected and analyzed samples of the participants' breast milk and blood before, during, and after the supplementation period to a... omega-3 development breast milk
Read moreDry eye disease – an inflammatory condition characterized by a stinging, burning, or scratchy sensation in the eyes – affects roughly 8 percent of adults in the U.S. Although several treatments address dry eye symptoms, none target the underlying inflammation. A recent systematic review and meta-analysis found that omega-3 fatty acids alleviate dry eye symptoms and reduce eye inflammation. Researchers reviewed the findings of randomized controlled trials investigating the effects of omega-3s on dry eye. Their analysis included 19 trials involving more than 4,200 patients. They found that the... omega-3 inflammation eyes
Read moreOmega-3 fatty acids are well-known for their effects on the immune system, brain function, and overall health. Recent studies suggest that these fatty acids also influence the body's internal clock, which regulates various biological processes. This review presents evidence that omega-3s may act as natural regulators of the body's internal clock, potentially benefiting conditions related to disrupted circadian rhythms. ... omega-3 circadian rhythm
Read moreOmega-3 supplementation in healthy humans increases several species of beneficial gut bacteria that produce short-chain fatty acids (double-blinded, randomized controlled trial). Supplementation with omega-3 PUFAs was associated with increased abundance of butyrate-producing ‘beneficial’, bacterial genera such as Bifidobacterium, Lachnospira, Roseburia, and Lactobacillus. An increase in SCFA-producing bacteria such as Bifidobacterium has been shown to reduce mucosal inflammatory tone in the gut. ... gut microbiome omega-3
Read moreCannabinoids (found in marijuana) are also are produced naturally by the body from omega-3 fatty acids where they fight inflammation. A new study in animal tissue finds a series of metabolic reactions that convert omega-3 fatty acids into cannabinoids that have anti-inflammatory benefits but without the psychotropic high. This is just one other mechanism by which omega-3 fatty acids produce anti-inflammatory benefits. ... omega-3 inflammation
Read moreOmega-3 and vitamin B12 supplementation in rats increased nerve growth factor (NGF), which helps grow new brain cells and boosts acetylcholine levels and improved cognitive performance after 2 generations in rats. The omega-3 and B12 also increased brain-derived neurotrophic factor (BDNF) and vascular endothelial growth factor (VEGF) which both also help grow new brain cells and maintain the blood-brain barrier. ... brain nootropics omega-3 vitamin b12 neurotransmitter acetylcholine vitamin a
Read more