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        [Story] Higher folate levels during pregnancy may protect against lead&#39;s neurotoxic effects, potentially reducing risk of autism-like behaviors in children.
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      Lead exposure during pregnancy can harm a child’s developing brain, increasing the risk of autism-related behaviors. Some evidence suggests that folate, a B vitamin, might help protect against lead&#39;s neurotoxic effects. A recent study found that higher folate levels during pregnancy may help reduce the risk of autism-like behaviors in children exposed to lead before birth.
Researchers analyzed data from a large mother-infant cohort study that tracked participants from pregnancy through early childhood. They measured blood lead levels and plasma folate concentrations during the women&#39;s first an...
          <span class="search-tag">brain</span>
          <span class="search-tag">pregnancy</span>
          <span class="search-tag">micronutrients</span>
          <span class="search-tag">genetics</span>
          <span class="search-tag">development</span>
          <span class="search-tag">folate</span>
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        [Story] Children exposed to skincare lotions and oils have higher urinary phthalate levels—known endocrine disruptors—even when products are labeled &quot;phthalate-free.&quot;
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      The lotion you apply to your child&#39;s skin might do more harm than good, according to new research. Children are especially vulnerable to harmful exposures through their skin because they have more skin surface area relative to their body size, better blood flow, and higher skin hydration than adults. A recent study found that using skincare lotions and oils significantly increased toxic phthalates in children&#39;s urine.
Researchers surveyed parents of children aged 4 to 8 about their children&#39;s use of skincare products and then tested the children&#39;s urine for phthalates. 
They discovered that ch...
          <span class="search-tag">pollution</span>
          <span class="search-tag">skin</span>
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        [Podcast] Why Exercise Intensity Matters for Longevity | CrossFit for Health 2024 
      </h3>
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      This is my keynote presentation from the 2024 CrossFit Health Summit where I explored how vigorous exercise and heat stress contribute to longevity.
...
          <span class="search-tag">exercise</span>
          <span class="search-tag">heat stress</span>
          <span class="search-tag">sauna</span>
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        [Story] Sleep deprivation leads to fatal accumulation of oxidative stress in the gut, but antioxidant diet can extend lifespan.
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      Sleep – a state that renders animals stationary and less responsive to stimuli – is crucial for survival. Some evidence suggests that sleep is important because it protects the body against harmful oxidative stress. A 2020 study in flies and mice showed that reactive oxygen species, which drive oxidative stress, accumulate in the gut during sleep deprivation, leading to death. 
Researchers deprived flies and mice of sleep for various durations, occasionally allowing them to sleep. Then, they measured reactive oxygen species in the animals&#39; tissues, including the heart, brain, muscles, and gut....
          <span class="search-tag">gut</span>
          <span class="search-tag">sleep</span>
          <span class="search-tag">antioxidant</span>
          <span class="search-tag">oxidative stress</span>
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        [Story] Apolipoprotein ɛ4-Associated Protection Against Pediatric Enteric Infections is a Survival Advantage in Pre-Industrial Populations
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      This 2023 review describes evidence suggesting that APOE4, a gene associated with a higher risk of Alzheimer&#39;s disease later in life, confers resistance to gut infections in children – a robust contributor to high childhood mortality. This dual nature of APOE4 may be an example of antagonistic pleiotropy, a theoretical construct that asserts that when a gene has two or more effects – with one beneficial and the other harmful – the beneficial one exerts its effects early in life, while the harmful one takes a toll later.
...
          <span class="search-tag">alzheimer&#39;s</span>
          <span class="search-tag">evolution</span>
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        [Story] Exercise offsets the life-shortening effects of poor sleep.
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      Getting too much sleep, having difficulty falling asleep, or taking sleeping pills dramatically increases a person&#39;s risk of premature death, a 2022 study found. But getting plenty of exercise offsets this risk, effectively canceling out the harms of poor sleep patterns. 
Researchers tracked the health, physical activity, and sleep patterns of more than 340,000 adults for 15 years. They calculated the metabolic equivalent (MET) of the participants&#39; physical activity – a ratio of their working metabolic rate relative to their resting metabolic rate. (For example, bicycling at a moderate pace (1...
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        [Podcast] Dr. Eran Elinav: Microbiome Insights into Personalized Response to Diet, Obesity, and Leaky Gut
      </h3>
</a>    <p>
      Dr. Eran Elinav discusses the complex interactions between humans and their resident gut microbiomes.
...
          <span class="search-tag">microbiome</span>
          <span class="search-tag">obesity</span>
          <span class="search-tag">metabolism</span>
          <span class="search-tag">heart disease</span>
          <span class="search-tag">diabetes</span>
          <span class="search-tag">intestinal permeability</span>
          <span class="search-tag">autoimmunity</span>
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        [Topic] Cold exposure
      </h3>
</a>    <p>
      [toc position=&#39;left&#39;]
Introduction
[tweetbox text=&#39;&quot;The beneficial effects of cold exposure may be due to hormesis, a favorable biological response to a mild stressor.&quot;&#39; tweet=&#39;&quot;The beneficial effects of cold exposure may be due to hormesis, a favorable biological response to a mild stressor.&quot; https://www.foundmyfitness.com/topics/cold-exposure-therapy&#39;]
Cold exposure to promote good health is an ancient practice, now used to reduce muscle soreness and promote muscle recovery after physical activity. However, regular cold exposure may also improve glucose and lipid metabolism, decrease inflamm...
          <span class="search-tag">performance</span>
          <span class="search-tag">cholesterol</span>
          <span class="search-tag">immune system</span>
          <span class="search-tag">thermogenesis</span>
          <span class="search-tag">cold stress</span>
          <span class="search-tag">brain</span>
          <span class="search-tag">heart disease</span>
          <span class="search-tag">diabetes</span>
          <span class="search-tag">insulin resistance</span>
          <span class="search-tag">inflammation</span>
          <span class="search-tag">depression</span>
          <span class="search-tag">mitochondria</span>
          <span class="search-tag">neuron</span>
          <span class="search-tag">blood pressure</span>
          <span class="search-tag">interesting</span>
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        [Podcast] Dr. Valter Longo on Resetting Autoimmunity and Rejuvenating Systems with Prolonged Fasting &amp; the FMD
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</a>    <p>
      Dr. Valter Longo discusses fasting as a means to treat or prevent age-related diseases such as cancer, Alzheimer’s disease, and others. 
...
          <span class="search-tag">fasting</span>
          <span class="search-tag">cancer</span>
          <span class="search-tag">obesity</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">heart disease</span>
          <span class="search-tag">diabetes</span>
          <span class="search-tag">insulin resistance</span>
          <span class="search-tag">inflammation</span>
          <span class="search-tag">stem cells</span>
          <span class="search-tag">immune system</span>
          <span class="search-tag">tissue repair</span>
          <span class="search-tag">autophagy</span>
          <span class="search-tag">apoptosis</span>
          <span class="search-tag">insulin</span>
          <span class="search-tag">autoimmunity</span>
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