A medical procedure used to remove harmful antibodies and lipids from the blood may have an unexpected additional target: persistent environmental pollutants. A new study asked whether apheresis could lower circulating microplastics and per- and polyfluoroalkyl substances (PFAS), often called "forever chemicals." Adults already scheduled for medically indicated apheresis provided blood samples immediately before and after treatment. In 14 people, researchers measured four PFAS. A second laboratory measured a wider PFAS panel in four people. Micro- and nanoplastic-associated signals were asses... Microplastics PFAS pollution
Read moreScientists have proposed many ways to measure biological aging, but it is still unclear which markers best predict hard outcomes such as death. A new study tested 14 aging biomarkers side by side to see which were most strongly associated with mortality. The researchers analyzed data from 1,671 adults in the Berlin Aging Study II who were 60 to 80 years old at the start of the study. The biomarkers included inflammatory and hormone-related blood measures, physical function tests, cognitive performance, blood pressure, and DunedinPACE, an epigenetic score that uses chemical tags on DNA measure... aging epigenetics mortality
Read moreDr. Rhonda Patrick and Dr. Arthur Brooks explore the science of happiness and how to live a more meaningful life. ... mental health anxiety social media stress behavior meditation dopamine brain depression
Watch nowResearch demonstrates that inflammation in later life harms the brain, increasing the risk of dementia and cognitive decline. However, scientists don't fully understand the effects of inflammation that begins in early adulthood. A recent study found that inflammation during early adulthood markedly impairs cognitive performance in midlife. The research involved more than 2,300 young adults (aged 24 to 58) enrolled in the Coronary Artery Risk Development in Young Adults (https://www.cardia.dopm.uab.edu) study. Researchers tracked the participants' inflammation levels, measured by C-reactive pro... brain alzheimer's aging inflammation memory dementia
Read moreDr. Martin Gibala discusses HIIT's health benefits and describes common HIIT protocols. ... exercise aging heart disease diabetes mitochondria cortisol fat muscle bone lactate exercise snacks
Watch nowDr. Morgan Levine discusses epigenetics and the application of epigenetic aging clocks in quantifying human aging. ... epigenetics cancer aging inflammation senescence
Watch nowEndurance and resistance training are associated with distinct hormonal signatures Exercise is widely accepted to be beneficial to our health. Research finds it to have a positive dose-dependent impact (https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-020-09855-3) on factors varying from cognitive function and bone strength to all-cause mortality and metabolic health. But does the specific mode of exercise make a difference? A 2018 study suggests that resistance and endurance exercise engage largely distinct hormonal responses in the body. It also highlights endurance trainin... exercise metabolism hormones fgf21
Read moreFor decades, deficiencies in micronutrients such as magnesium (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783146/) and vitamin D (https://pubmed.ncbi.nlm.nih.gov/18652680/) have been linked to conditions such as depression (https://www.ncbi.nlm.nih.gov/books/NBK507265/) and obesity (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780345/), as well as their associated hallmarks of systemic inflammation (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079193/). These observations raise questions about whether certain nutritional inadequacies might play a causal role in these conditions and whethe... vitamin d obesity inflammation depression magnesium il-6
Read moreGlioma is a collective term for tumors that arise from the glial cells in the brain. Astrocytoma, the most common form of glioma, arises from star-shaped cells in the brain called astrocytes. The the survival rate for glioma, including astrocytoma, is low. Findings from a recent study suggest that a ketogenic diet is beneficial for people with astrocytoma. Ketogenic diets are low in carbohydrates and high in proteins and fats. They cause the body to oxidize fats to produce ketones for energy. For many years, ketogenic diets have been used in the clinical setting to reduce seizures in children... cancer ketosis ketogenic diet
Read moreCOVID-19 Q&A Part 2: Rhonda Patrick, Ph.D. answers subscriber questions in a multi-part series. ... covid-19 vitamin d nutrition exercise microbiome sleep vitamin c omega-3 inflammation immune system virus micronutrients vitamin e vaccine genetics testosterone estrogen zinc fiber autoimmunity
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