[toc] Alcohol is one of the most heavily used and abused drugs. It's also a very controversial topic, in part because alcohol plays such a large role in societies and cultures around the world. For many, it's a normal part of daily life. There is also a lot of confusion about alcohol. There's no doubt that alcohol can have a personal and public health impact. On the other hand, research in the last few decades suggests that not only may a moderate intake of alcohol not be harmful, but it might also be protective against certain diseases. This idea is heavily debated, and conflicting evidence h... cancer cardiovascular alcohol brain alzheimer's diabetes breast cancer
Read more[toc position='left'] Protein is one of nutrition's most essential and debated topics. It goes far beyond its reputation as the building block of muscle, playing a crucial role in metabolism, insulin sensitivity, and the prevention of diseases like type 2 diabetes and sarcopenia. But questions abound: How much protein is enough, and can too much, particularly from animal sources, be harmful? Protein intake, paired with resistance training, drives muscle repair and growth, enhancing athletic performance, improving metabolic health, and promoting longevity by protecting against age-related frai... protein nutrition muscle exercise aging strength
Read moreMaternal nutrition during pregnancy plays a critical role in a child's development. A new study suggests that low dietary fiber intake during pregnancy harms neurodevelopment. Children of women who consumed lower levels of dietary fiber during pregnancy were nearly 50 percent more likely to experience developmental delays. The study involved more than 76,000 Japanese mother-infant pairs. The women completed questionnaires about their typical dietary intake and supplement use during their pregnancies and then provided information about their child's development at the age of three years. The q... nutrition diet pregnancy development fiber
Read moreEstrogen mitigates the association between visceral fat on cognitive decline. Estradiol, a form of estrogen, is the primary female sex hormone. It participates in menstrual cycle regulation and drives the development of female secondary sex characteristics, such as breasts, a wider pelvis, and gynoid fat – fat that forms around the hips, thighs, and breasts. Evidence suggests that estradiol exerts both cardioprotective (https://pubmed.ncbi.nlm.nih.gov/12893838/) and neuroprotective (https://pubmed.ncbi.nlm.nih.gov/11040417/) effects. Findings from a 2020 study demonstrate that estradiol mitig... brain alzheimer's obesity memory estrogen visceral fat
Read more[toc position='left'] Background Berberine is an alkaloid compound present in the roots, stems, rhizomes, and bark of a variety of plants, including Californian poppy, goldenseal, cork tree, Chinese goldthread, Oregon grape, and several plants in the Berberis genus. It is also widely available as a dietary supplement. Berberine has a long history of use in the ancient and traditional medicine systems of India, China, and Persia. Research demonstrates that berberine may exert pharmacological effects against certain chronic health conditions such as cardiovascular disease, gastrointestinal disor... exercise brain parkinson's depression aging diabetes heart disease fatty liver
Read moreA randomized controlled trial found 4 common chemical sunscreens (avobenzone, oxybenzone, octocrylene, and ecamsule) were absorbed into the bloodstream at concentrations above the FDA's potential toxicological threshold. Some of the chemical sunscreen ingredients stayed in plasma up to 3 days after they were applied to the skin. It is unclear whether these ingredients have any harmful effects on human health. However, since their levels exceed the FDA threshold that means more tests on cancer, endocrine effects and more will be required to be tested by the FDA. Here is a good wired article tha...
Read moreFTA: > In summary, DOX is a very valuable cancer chemotherapeutic drug that frequently results in severe cardiomyopathy. The ability of SFN to protect against DOX cardiotoxicity, as shown for the first time by the results of our study, is a discovery that could significantly change the way DOX is currently used. Our findings not only provide further insight into DOX-induced cardiotoxicity, but especially demonstrate SFN action through the Keap1/Nrf2 signaling pathway for countering cardiac damage. Our observations should establish the basis for devising novel approaches to protect the human... abstract cancer heart disease drug sulforaphane nrf2
Read moreFTA: >"We know that the permeability of the intestines to harmful substances is raised in inflammatory bowel diseases such as Crohn's disease and ulcerous colitis, as well as in some other autoimmune diseases such as type 1 diabetes. The condition is called 'leaky gut syndrome'. Our studies indicate a leaky gut and increased inflammation in the intestinal mucous membrane and related lymphoid tissue before clinical symptoms of MS are discernible. It also appears that the inflammation increases as the disease develops", said Shahram Lavasani, one of the authors of the study. Dr Lavasani and h... gut inflammation multiple sclerosis autoimmunity
Read more