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        [Podcast] Q&amp;A #77: What’s the Best Time to Exercise?—Morning vs. Evening and How to Sequence Sauna and Cold
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      Dr. Rhonda Patrick discusses supplement timing, exercise timing, supplements in older adults, folic acid vs. folate, and hydrogen-rich water.
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        [Podcast] How Supplements May Support Brain Health With Age
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      Dr. Rhonda Patrick reviews multivitamins, vitamin D, omega-3s, ubiquinol, and sulforaphane in the context of her parents’ health.
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        [Podcast] Aliquot #128: The Expanding Role of Weight Loss Drugs
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      In this Aliquot, I discuss how these drugs work, their pros and cons, the latest research, and lifestyle strategies to...
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        [Podcast] Q&amp;A #68: Are Natural and Artificial Flavors Harmful?—Plus Saturated Fat &amp; LDL
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      Dr. Rhonda Patrick discusses saturated fats and LDL, luteolin&#39;s benefits, glyphosate risks, natural vs. artificial flavors, and black cumin seed effects.
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        [Podcast] Q&amp;A #58: High-Dose Niacin, NAD+ Boosters, &amp; Cardiovascular Risk
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      Dr. Rhonda Patrick explores collagen peptides, high-dose niacin and vitamin B6, avoiding nano- and microplastics in her latest Q&amp;amp;A.
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        [Podcast] Q&amp;A #44: Should You Take NAC Daily—and Does Fish Oil Raise LDL?
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      Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&amp;amp;A session.
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        [Podcast] Aliquot #77: Managing migraine frequency and pain with lifestyle
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      Migraine is a neurological disorder that typically manifests as an intense, debilitating headache and is often accompanied by nausea, vomiting, and light sen...
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        [Podcast] Q&amp;A #11: What Prevents Migraines—and How Do Heat and Cold Affect Health?
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      Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&amp;amp;A session.
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        [Topic] Nicotinamide mononucleotide
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Nicotinamide mononucleotide (NMN) is a precursor molecule for the biosynthesis of nicotinamide adenine dinucleotide, or NAD+, a coenzyme that participates in the production of cellular energy and DNA repair. NAD+ can also be synthesized from other precursors including nicotinamide (NAM, also called niacinamide), nicotinic acid (NA), and nicotinamide riboside (NR), which are often collectively referred to as niacin (vitamin B3) or niacin equivalents.[ref doi=&#39;10.12688/f1000research.12120.1&#39;] These precursors are not equally allocated throughout the body; rather, they exhib...
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        [Topic] Sirtuins
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Sirtuins are highly conserved enzymes that play key roles in healthspan and longevity in multiple organisms. They are linked to the regulation of a variety of metabolic processes, including the release of insulin, mobilization of lipids, response to stress, and modulation of lifespan.[ref doi=&#39;10.1016/j.tem.2013.12.001&#39;] [ref doi=&#39;10.1016/j.bbapap.2009.11.021&#39;] Sirtuins have been implicated in the pathophysiology of metabolic disorders such as type 2 diabetes; neurological disorders such as Parkinson’s disease; and many other conditions related to aging.[ref doi=&#39;10.3389/...
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