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        [Topic] Biological Age Clocks
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Biological aging clocks are among the most important tools in modern longevity science. They attempt to answer a deceptively simple question: can we measure how fast a person is aging biologically, rather than just counting the number of years they have been alive?
The answer is yes—but with important caveats.
Epigenetic clocks use patterns of DNA methylation, a chemical tagging system on DNA, to estimate different aspects of aging. Some clocks estimate chronological age. Others predict disease risk, mortality risk, or the current pace of biological aging. This means biol...
          <span class="search-tag">epigenetics</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">telomeres</span>
          <span class="search-tag">genetics</span>
          <span class="search-tag">stem cells</span>
          <span class="search-tag">omega-3</span>
          <span class="search-tag">dna damage</span>
          <span class="search-tag">biomarkers</span>
          <span class="search-tag">vitamin d</span>
          <span class="search-tag">senescence</span>
          <span class="search-tag">multivitamin</span>
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        [Podcast] Q&amp;A #76: How Much Protein Do You Need—and Is Nightly Melatonin Safe?
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      Dr. Rhonda Patrick discusses protein needs, choline in pregnancy, urolithin A, melatonin&#39;s benefits and risks, and creatine&#39;s effects on liver health.
...
          <span class="search-tag">rhonda</span>
          <span class="search-tag">pregnancy</span>
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          <span class="search-tag">melatonin</span>
          <span class="search-tag">fatty liver</span>
          <span class="search-tag">urolithin a</span>
          <span class="search-tag">creatine</span>
          <span class="search-tag">choline</span>
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        [Podcast] Dr. Ben Bikman: How To Reverse Insulin Resistance Through Diet, Exercise, &amp; Sleep
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      Dr. Ben Bikman and Rhonda Patrick discuss the primary causes of insulin resistance and how to reverse it in as little as 90 days.
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          <span class="search-tag">insulin resistance</span>
          <span class="search-tag">insulin</span>
          <span class="search-tag">blood sugar</span>
          <span class="search-tag">diabetes</span>
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        [Topic] Alcohol
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Alcohol is one of the most heavily used and abused drugs. It&#39;s also a very controversial topic, in part because alcohol plays such a large role in societies and cultures around the world. For many, it&#39;s a normal part of daily life.
There is also a lot of confusion about alcohol. There&#39;s no doubt that alcohol can have a personal and public health impact. On the other hand, research in the last few decades suggests that not only may a moderate intake of alcohol not be harmful, but it might also be protective against certain diseases. This idea is heavily debated, and conflicting evidence h...
          <span class="search-tag">cancer</span>
          <span class="search-tag">cardiovascular</span>
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          <span class="search-tag">brain</span>
          <span class="search-tag">alzheimer&#39;s</span>
          <span class="search-tag">diabetes</span>
          <span class="search-tag">breast cancer</span>
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        [Podcast] Q&amp;A #56: Ozempic for Weight Loss—Muscle Loss, Side Effects, &amp; Weight Regain
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      Dr. Rhonda Patrick explores creatine, dairy&#39;s effect on polyphenols, eggs&#39; health impact, and new weight loss drugs like Ozempic in her latest Q&amp;amp;A.
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          <span class="search-tag">rhonda</span>
          <span class="search-tag">vitamin d</span>
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          <span class="search-tag">protein</span>
          <span class="search-tag">polyphenol</span>
          <span class="search-tag">red light therapy</span>
          <span class="search-tag">Hair</span>
          <span class="search-tag">GLP-1</span>
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        [Topic] Sulforaphane
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Sulforaphane is a bioactive compound derived from certain cruciferous vegetables, particularly broccoli (and its sprouts) and red kale. Robust evidence from epidemiological, clinical, rodent, and in vitro studies has demonstrated that sulforaphane exhibits antioxidant and anti-inflammatory properties and may be beneficial against a wide range of chronic and acute diseases, including autism, cancer, metabolic dysfunction, and many others and may ameliorate some of the harmful effects associated with exposure to air pollution.  
Sulforaphane exerts its therapeutic effects t...
          <span class="search-tag">sulforaphane</span>
          <span class="search-tag">cancer</span>
          <span class="search-tag">behavior</span>
          <span class="search-tag">supplements</span>
          <span class="search-tag">brain</span>
          <span class="search-tag">breast cancer</span>
          <span class="search-tag">inflammation</span>
          <span class="search-tag">autism</span>
          <span class="search-tag">antioxidant</span>
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        [Story] A high saturated fat diet increases heart disease marker, TMAO.
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      Heart disease is the number one cause of death in the United States, owing to a constellation of risk factors including a sedentary lifestyle, disrupted sleep patterns, stress, and poor diet. The average American adult consumes 29 grams of saturated fat per day (https://www.ars.usda.gov/northeast-area/beltsville-md-bhnrc/beltsville-human-nutrition-research-center/food-surveys-research-group/docs/wweia-data-tables/) (the amount in about four tablespoons of butter, four slices of pepperoni pizza, or 1.5 cups of ice cream), possibly contributing to heart disease risk through interactions with the...
          <span class="search-tag">microbiome</span>
          <span class="search-tag">heart disease</span>
          <span class="search-tag">fat</span>
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        [Story] Vitamin K benefits heart health.
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      Heart disease, including atheroslcerotic cardiovascular disease, is a leading cause of death worldwide. Its associated inflammation and metabolic dysfunction can be prevented with a diet high in nutrient dense foods such as those commonly found in the Mediterranean diet (https://www.mdpi.com/1422-0067/20/19/4716). Findings of a new report indicate that a high intake of vitamin K - a micronutrient found at high levels in common Mediterranean meals - might reduce the incidence of atherosclerotic disease.
Atherosclerosis refers to the hardening of arteries due to the formation of plaques composed...
          <span class="search-tag">heart disease</span>
          <span class="search-tag">vitamin k</span>
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        [Podcast] Q&amp;A #25: COVID-19 Vaccines—Spike Protein, Ivermectin, &amp; Pregnancy
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      Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&amp;amp;A session.
...
          <span class="search-tag">rhonda</span>
          <span class="search-tag">vitamin d</span>
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          <span class="search-tag">vaccine</span>
          <span class="search-tag">skin</span>
          <span class="search-tag">zinc</span>
          <span class="search-tag">time-restricted eating</span>
          <span class="search-tag">blood sugar</span>
          <span class="search-tag">covid-19</span>
          <span class="search-tag">breast milk</span>
          <span class="search-tag">Hair</span>
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        [Topic] NAD+
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Nicotinamide adenine dinucleotide (NAD+) is a cofactor (a molecule that assists enzymes in chemical reactions) that plays an essential role in multiple physiological processes, such as energy metabolism, DNA repair, and immune activation. It is necessary for the activity of sirtuins, a class of enzymes involved in longevity, and poly-ADP-ribose polymerases (PARPs), a family of DNA-repair enzymes. Cellular NAD+ production declines with age, however, and its depletion likely drives the onset and progression of multiple age-related conditions such as metabolic dysregulation ...
          <span class="search-tag">metabolism</span>
          <span class="search-tag">mitochondria</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">dna damage</span>
          <span class="search-tag">circadian rhythm</span>
          <span class="search-tag">nad+</span>
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