Q&A #76 with Dr. Rhonda Patrick (12/06/25)

        *   00:01:23 - Q: Are nicotinamide and niacinamide the same molecule? 
*   00:01:47 - Q: Is creatine safe for liver health? [1](https://link.springer.com/article/10.1007/s00726-011-0878-2),[2](https://link.springer.com/article/10.1007/s00726-016-2183-6),[3](https://www.sciencedirect.com/science/article/pii/S0024320522007640) 
*   00:06:19 - Q: Do Rhonda and Peter Attia differ on protein recommendations? [1](https://www.sciencedirect.com/science/article/pii/S216183132201225X),[2](https://pubmed.ncbi.nlm.nih.gov/28698222/),[3](https://journals.lww.com/nsca-scj/fulltext/2020/10000/body_recomposition__can_trained_individuals_build.3.aspx)
*   00:16:28 - Q: How does individual context shape protein needs?
*   00:17:32 - Q: Do people on plant-based diets require more protein?
*   00:18:20 - Q: Is there value in taking free-form amino acids? [1](https://www.mdpi.com/1422-0067/26/23/11264),[2](https://doi.org/10.1016/j.clnu.2023.08.010),[3](https://www.tandfonline.com/doi/full/10.1080/15502783.2023.2263409)
*   00:29:15 - Q: Do you prefer whey or pumpkin seed protein?
*   00:29:52 - Q: What's Rhonda's pick for a "clean" protein powder?
*   00:30:49 - Q: Can egg white protein replace whey for sensitive individuals?
*   00:31:05 - Q: Is stevia a healthy sweetener for protein powders?
*   00:31:25 - Q: What form of choline is best during pregnancy? [1](https://faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202101217R)
*   00:33:59 - Q: How do EPA and DHA differ for brain health and antidepressant effects? [1](https://www.nature.com/articles/s41398-019-0515-5),[2](https://www.sciencedirect.com/science/article/pii/S1043661824002676),[3](https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2019.01696/full)
*   00:37:05 - Q: Can you test your urolithin A metabotype or natural production? [1](https://www.nature.com/articles/s41430-021-00950-1)
*   00:46:17 - Q: What brand and dose of urolithin A does Rhonda use?
*   00:48:35 - Q: What's the ideal maintenance dose of urolithin A?
*   00:51:07 - Q: Is there a heart failure risk with long-term melatonin use? [1](https://www.ahajournals.org/doi/10.1161/circ.152.suppl_3.4371606),[2](https://jcsm.aasm.org/doi/10.5664/jcsm.6462),[3](https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2022.888319/full)
*   01:07:45 - Q: Is nightly low-dose melatonin safe and beneficial? [1](https://link.springer.com/article/10.1007/s00280-012-1828-8),[2](https://onlinelibrary.wiley.com/doi/10.1111/jpi.12782),[3](https://link.springer.com/article/10.1007/s40263-019-00680-w)
*   01:10:45 - Q: Does supplemental melatonin suppress natural production? [1](https://pmc.ncbi.nlm.nih.gov/articles/PMC3150476/),[2](https://pubmed.ncbi.nlm.nih.gov/9062869/),[3](https://www.mdpi.com/2077-0383/11/17/5138)
*   01:13:06 - Q: Should a child in puberty take low-dose melatonin? [1](https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370%2823%2900260-2/fulltext),[2](https://pubmed.ncbi.nlm.nih.gov/29498667/)
*   01:17:13 - Q: Is later-onset puberty associated with better long-term health? [1](https://www.sciencedirect.com/science/article/pii/S2352827319303544),[2](https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2024.1326864/full)
*   01:18:04 - Q: When is hormone replacement therapy appropriate? [1](https://journals.lww.com/menopausejournal/abstract/2022/07000/the_2022_hormone_therapy_position_statement_of_the.4.aspx)