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        [Topic] Small vessel disease
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      ...he burden of lacunes, white matter hyperintensities, and other markers of small vessel disease.[ref doi=&#39;10.4065/mcp.2011.0252&#39;]
Low levels of plasma <span class="text-highlight">omega-3</span> polyunsaturated fatty acids were associated with more severe cerebral small vessel diseases in patients who had experienced an ischemic stroke....
          <span class="search-tag">small vessel disease</span>
          <span class="search-tag">brain</span>
          <span class="search-tag">alzheimer&#39;s</span>
          <span class="search-tag">vitamin d</span>
          <span class="search-tag">omega-3</span>
          <span class="search-tag">parkinson&#39;s</span>
          <span class="search-tag">inflammation</span>
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          <span class="search-tag">blood-brain barrier</span>
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        [Story] APOE4 carriers had a 4.92 higher odds of committing suicide in a high air pollution environment (mexico city)
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      ... People who carry the high-risk genetic variant APOE4 are at substantially greater risk and may, additionally, be vulnerable to greater suicide risk. <span class="text-highlight">Omega-3</span> fatty acids help maintain blood-brain barrier integrity (https://onlinelibrary.wiley.com/doi/full/10.1002/brb3.2273) and may reduce the risk of...
          <span class="search-tag">brain</span>
          <span class="search-tag">alzheimer&#39;s</span>
          <span class="search-tag">depression</span>
          <span class="search-tag">genetics</span>
          <span class="search-tag">pollution</span>
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        [Story] Apolipoprotein E is predictive of Alzheimer&#39;s risk even in individuals without the E4 allele
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      ...on in people with Alzheimer&#39;s disease. 
Interestingly, robust evidence suggests that APOE4 carriers have impaired brain transport of certain forms of <span class="text-highlight">omega-3</span> fatty acids, contributing to their risk of developing Alzheimer&#39;s disease. Learn more in this peer-reviewed article by Dr. Rhonda Patrick. (htt...
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        [Topic] Brain-derived neurotrophic factor (BDNF)
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      ...listid=&#39;25&#39; title=&#39;The BDNF Protocol Guide&#39; subtext=&#39;An essential checklist for cognitive longevity — filled with specific exercise, heat stress, and <span class="text-highlight">omega-3</span> protocols for boosting BDNF. Enter your email, and we&#39;ll deliver it straight to your inbox.&#39; buttontext=&#39;DOWNLOAD GUIDE&#39; success_text=&#39;Please c...
          <span class="search-tag">exercise</span>
          <span class="search-tag">omega-3</span>
          <span class="search-tag">meditation</span>
          <span class="search-tag">brain</span>
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          <span class="search-tag">fasting</span>
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          <span class="search-tag">interesting</span>
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        [Podcast] How sauna mimics cardiovascular exercise: a comparison to stationary bike | Rhonda Patrick
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      In this clip, Dr. Rhonda Patrick describes how the physiological effects observed during sauna use are comparable to those that occur during physical exercise.
...
          <span class="search-tag">exercise</span>
          <span class="search-tag">sauna</span>
          <span class="search-tag">blood pressure</span>
          <span class="search-tag">cardiovascular</span>
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        [Podcast] Sauna use and heat for strength preservation (anti-atrophy effect) | Rhonda Patrick
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      In this clip, Dr. Rhonda Patrick discusses how heat can be used to increase muscle strength and counteract muscle wasting.
...
          <span class="search-tag">exercise</span>
          <span class="search-tag">heat stress</span>
          <span class="search-tag">muscle</span>
          <span class="search-tag">sauna</span>
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        [Podcast] Timing metformin to avoid negative effects on exercise adaptation: plausibility | Rhonda Patrick
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      Dr. Rhonda Patrick discusses whether taking metformin apart from exercise could reduce some adverse effects on exercise adaptation.
...
          <span class="search-tag">exercise</span>
          <span class="search-tag">metformin</span>
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        [Story] Brain inflammation found to be 30% higher in people suffering with obsessive-compulsive disorder.
      </h3>
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      ...m these disorders, it does make multi-pronged inflammation reduction approaches that much more appealing.
This could possibly include...
supplemental <span class="text-highlight">omega-3</span> (especially supplements rich in EPA, which dampens inflammation)
supplemental sulforaphane which dampens inflammation and may also cross the bl...
          <span class="search-tag">brain</span>
          <span class="search-tag">omega-3</span>
          <span class="search-tag">inflammation</span>
          <span class="search-tag">depression</span>
          <span class="search-tag">immune system</span>
          <span class="search-tag">anxiety</span>
          <span class="search-tag">iron</span>
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