Some brain tumors remain incurable even after surgery, radiation, and chemotherapy and are often linked to a short life expectancy. To explore a potential new therapy, researchers analyzed long-term data from an earlier brain tumor vaccine trial to determine whether the treatment was associated with longer survival and improved tumor control. The original trial enrolled 33 adults with newly diagnosed astrocytoma, a brain tumor named for its resemblance to astrocytes, star-shaped cells that help support nerve cells by supplying nutrients and maintaining a healthy environment around them. Their... brain cancer immune system vaccine
Read moreMost exercise guidelines recommend resistance training, but they give little detail on how much may be optimal for longevity. In a new study, researchers investigated whether different self-reported amounts of weekly resistance training were linked to fewer deaths overall and from specific causes. The analysis included 147,374 adults from three long-running US studies of health professionals, including 31,540 men and 115,834 women. For the main analysis, researchers grouped participants by their average reported weekly resistance training into six categories, from none to 120 minutes or more ... exercise mortality muscle strength
Read moreWhen body weight returns after a weight-loss program, it can obscure whether more specific changes in body fat lasted and still matter for metabolic health. A new study asked whether changes in visceral fat, the fat stored deep around the abdominal organs, were more closely linked to long-term metabolic health than weight loss alone. The researchers followed mostly male participants with abdominal obesity or abnormal blood lipid levels from two earlier 18-month randomized lifestyle intervention trials designed to promote moderate weight loss through diet and physical activity. During those tri... diabetes visceral fat weight loss
Read moreExercise is known to support brain health, but the biological link between fitness and brain function is still being clarified. A new study tested whether improving cardiorespiratory fitness changes the brain-derived neurotrophic factor (BDNF, a protein involved in brain signaling) response to hard exercise and alters brain activity during cognitive tasks. In this randomized study, 49 sedentary adults aged 18 to 55 were enrolled, but the final analyses included only 20 to 23 participants due to dropouts and missing data. They were assigned to either a 12-week cycling program or to a control g... bdnf cognition exercise
Read moreMetabolic dysfunction-associated steatotic liver disease (MASLD) involves fat accumulation in the liver, but less is known about whether the underlying metabolic defects vary across the day. Researchers tested whether day–night differences in how the body handles sugar and fat could help explain why fat builds up in the liver. The study included 24 overweight adults: 12 with MASLD and 12 controls without MASLD. Participants did not have diabetes, and each completed separate daytime and nighttime testing visits after 12 hours of fasting. Researchers measured insulin sensitivity using the gold-... circadian rhythm fatty liver metabolism
Read moreHydrogen sulfide is a small signaling molecule that the body produces using sulfur-containing compounds. It helps cells respond to stress, generate energy, and regulate how proteins function. Researchers wanted to know whether increasing production of this molecule over time could promote healthy aging. The study included a long-term lifespan experiment in healthy male mice starting at 20 weeks of age. Their diet was supplemented with a garlic-derived mixture of diallyl sulfur compounds (molecules with two small carbon-containing "arms" linked by sulfur atoms). To isolate the role of individu... aging metabolism
Read moreDr. Rhonda Patrick discusses stroke risk, eczema, immune resilience, her new smoothie recipe, and whether everyone should cut out gluten. ... rhonda immune system cholesterol gluten sauna stroke intestinal permeability microbiome green tea L-Theanine
Watch nowIn this episode, we’re taking a deep dive into alcohol. We’ll explore the science, misconceptions, controversies, and health effects of this widely used drug. ... alcohol exercise brain alzheimer's cancer aging microbiome sleep heart disease
Watch nowPhysical activity is perhaps the most important lifestyle factor in the promotion of heart health because of the beneficial stress it puts on the heart. Sauna bathing (https://foundmyfitness.com/topics/sauna) puts similar stress on the heart by increasing cardiac output in an effort to cool the body, making it a good choice for people unable to meet exercise guidelines; however, people who combine activities may experience unique benefits. Findings from a report released this month demonstrate the robust beneficial effects of combined physical activity and sauna bathing on cardiovascular fitne... exercise sauna cardiovascular
Read moreIn this clip, Dr. Rhonda Patrick discusses what cross-immunity is and how it may be relevant for SARS-CoV-2. ... covid-19 immune system virus
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