The brain's cleanup system, often called the glymphatic system, uses the movement of cerebrospinal fluid to help carry waste away from brain tissue. That process is best known for its activity during sleep, but less is known about how brain fluid moves during wakefulness. A new study tested whether movement-related contractions of the abdominal muscles (the muscles in the belly wall) could create pressure changes that reach the brain and shift those fluids. The researchers studied mice while they moved on a spherical treadmill, using high-speed brain imaging to track tiny shifts in the top su... alzheimer's dementia exercise
Read more[toc position='left'] Choline is an essential nutrient critical for various bodily functions, including brain development, liver health, and muscle function. It acts as a precursor to acetylcholine, a neurotransmitter involved in memory, attention, and muscle control. Choline also contributes to the synthesis of phospholipid membranes and serves as a source of methyl groups necessary for metabolic processes. While the body can produce small amounts of choline, most of it must come from the diet to meet physiological needs. The benefits of choline are wide-ranging. During pregnancy, adequate ch... brain blood-brain barrier alzheimer's acetylcholine
Read moreDr. Peter Attia presents practical steps we can implement to improve our health, emphasizing the importance of each aspect while providing actionable advice. ... aging cancer metabolism
Watch now[toc position='left'] Aging refers to the collective physiological, functional, and mental changes that accrue in a biological organism over time. The hallmarks of aging are observable biological patterns of dysfunction that occur with aging. Integral to the aging process is inflammaging, the chronic, low-grade inflammation that occurs with aging.[ref doi='10.1111/j.1749-6632.2000.tb06651.x'] The mechanisms that drive inflammaging and the pathological conditions that arise because of it are bidirectional and involve multiple physiological processes and pathways, many of which directly or indir... mitochondria aging omega-3 stem cells aerobic senescence
Read moreIn this clip, Dr. Rhonda Patrick discusses the current sulforaphane research as it pertains to DNA damage, and highlights the importance of considering the different forms of studies. ... sulforaphane dna damage antioxidant nrf2
Watch nowIn this clip, Dr. Rhonda Patrick explains that while magnesium L-threonate has yielded promising results in animal studies, this has yet to be translated to humans. ... magnesium brain
Watch nowThis clip originates from an interview recorded on the Kevin Rose Show, which you can click here to download the full version of. (https://podcasts.apple.com/us/podcast/dr-rhonda-patrick-new-omega3-sulforaphane-research/id1088864895?i=1000461297039) Metformin, a drug commonly used to treat type 2 diabetes, has garnered interest as a longevity compound because it was shown to extend lifespan in some animal models. These effects are variable and seem to depend on the age and gender of the animals, as well as the dose provided. Most of the lifespan-extending benefits have been observed in female ... aging diabetes metformin
Watch nowDr. Rhonda Patrick makes her fifth appearance on the Joe Rogan Experience. ... nutrition vitamin d metabolism diabetes telomeres omega-3 inflammation depression dna damage stem cells micronutrients mitochondria autophagy autism schizophrenia resveratrol sulforaphane insulin blue light
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