Dr. Rhonda Patrick and Dr. Steve Horvath discuss how epigenetic clocks measure biological age and which proven interventions actually slow or reverse aging. ... epigenetics telomeres genetics stem cells omega-3 dna damage biomarkers aging vitamin d senescence multivitamin
Watch nowDr. Rhonda Patrick and Dr. Charles Brenner discuss NAD precursors, NR versus NMN, NAD IV drips, and what truly boosts NAD for recovery and longevity. ... nad+ pregnancy dna damage aging resveratrol oxidative stress
Watch nowWhen a tooth infection spreads to the root, the body's immune response can become overly aggressive, destroying surrounding bone and tissue. Scientists at São Paulo State University tested whether two accessible lifestyle factors, swimming and omega-3 fatty acids, could reduce this damage. Thirty male rats were divided into three groups: an exercise‑only group, a group that combined exercise with omega-3 supplementation, and a control group without exercise or omega-3 supplementation. The exercising rats swam for an hour a day, five days a week, for six weeks. The combined group also received... exercise omega-3 dental
Read moreDrs. Andy Galpin and Rhonda Patrick discuss glutamine as fuel for immune and gut cells and explain how they use it in practice. ... supplements immune system gut intestinal permeability
Watch nowDr. Andy Galpin & Dr. Rhonda Patrick discuss nutrition, supplement, and recovery strategies for improving exercise performance. ... exercise supplements nutrition sleep performance omega-3 vitamin e heat stress cold stress iron protein
Watch nowAlthough inflammation is a critical component of the body's immune response, excess inflammation drives many chronic diseases, such as autoimmune disorders, cardiovascular diseases, diabetes, and cancer. A new study in mice shows that regular exercise reprograms macrophages, altering how they sense and respond to pathogens and reducing inflammation. Macrophages are immune cells that participate in pathogen elimination via phagocytosis. Distinguished by their polarization, "M1" macrophages exhibit a proinflammatory phenotype, while "M2" macrophages exhibit an anti-inflammatory phenotype. A hig... exercise inflammation immune system mitochondria
Read moreThis 2023 study found that exercise dampened inflammatory pathways and restored immune function in old animals. ... exercise aging inflammation stem cells
Read moreLactate is a compound that is produced primarily in the muscles via the breakdown of glucose during exercise. It can be "shuttled" from the muscles to various tissues, including the heart, and brain, where it can be used as an energy source. Evidence from a recent study suggests that lactate rejuvenates immune cells that target cancer. Specialized immune cells called CD8+ T cells are the primary drivers of anti-tumor immunity. During cancer progression, CD8+ T cells can experience "exhaustion," (https://www.frontiersin.org/articles/10.3389/fimmu.2020.622509/full) a dysfunctional state caused ... exercise cancer lactate
Read moreFrom the article: >Another Reason to Work Out Results showed that the ratio of senescent to naïve T cells changed favorably in the majority of participants, with most of the study subjects regaining greater numbers of the naïve variety. >"What we're suggesting is that with exercise, you might be getting rid of T cells that aren't helpful and making room for T cells that might be helpful," Bilek says. ... exercise cancer immune system
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