Dr. Peter Attia presents practical steps we can implement to improve our health, emphasizing the importance of each aspect while providing actionable advice. ... aging cancer metabolism
Watch nowIntense aerobic exercise reduces the risk of metastatic cancer by as much as 73 percent, a recent study has found. It does this by reducing the glucose consumption of the body's internal organs, effectively diverting energy away from the tumor. Researchers quantified the proteins present in the internal organs of mice and the plasma of humans and found that exercise alters multiple aspects of metabolism, including glucose uptake, mitochondrial activity, and carbohydrate utilization. Then they analyzed data from a long-term study of more than 2,700 adults living in Israel. They found that hig... exercise cancer
Read moreStress ages the immune system. Psychosocial stress, such as that experienced with discrimination or trauma, has profound effects on the human body. For example, evidence suggests that stress alters the immune system, driving inflammatory processes and impairing antiviral responses (https://pubmed.ncbi.nlm.nih.gov/21928900/). Findings from a recent study demonstrate that stress accelerates immune aging. Immune function wanes as the body ages, a phenomenon referred to as immunosenescence. This gradual deterioration of the immune system is widely considered the primary driver of the increased r... aging immune system stress
Read moreDr. Ashley Mason discusses the practice of cognitive behavioral therapy and sauna use in treating depression. ... sauna brain depression behavior mental health
Watch nowJust one night of sleep deprivation can impair arterial function, and chronically poor sleep increases the risk of developing cardiovascular disease. Conversely, high intensity interval exercise can improve multiple markers of heart health. In this report, researchers tested the effects of exercise on flow mediated dilation, a measure of vascular function, in sleep-deprived participants. Flow mediated dilation is a measure of how wide an artery expands in response to increased blood flow. Meals high in fat normally cause dysfunction in blood vessels, impairing their ability to dilate. Previous... exercise heart disease cardiovascular
Read moreOral quercetin supplementation may blunt exercise-induced muscle adaptations (animal study). Exercise induces the formation of reactive oxygen species (ROS), which, in excess, can promote muscle damage, fatigue, and immune dysfunction. However, ROS may also mediate beneficial training adaptations as a part of a biologically useful signaling cascade. A study from 2013 found that quercetin, a bioactive compound that exerts anti-inflammatory and antioxidant effects, blunts exercise induced skeletal muscle adaptations in rats. Quercetin is both a direct and indirect antioxidant, meaning it scaveng...
Read moreExercise elicits a wide range of physiological changes in the body that improve multiple aspects of cardiovascular, neurological, and metabolic health. The molecular mechanisms that drive these improvements are not well understood. Findings from a new study suggest that an acute bout of aerobic exercise alters more than 9,000 distinct molecules in the human body to positively influence health. The study involved 36 adults between the ages of 40 and 75 years. The average body mass index among the participants was 28, which is considered overweight. Their steady-state blood glucose levels range... exercise insulin resistance inflammation
Read moreAcute respiratory distress syndrome (ARDS) is a severe form of acute lung injury, characterized by rapid breathing, shortness of breath, and a low blood oxygen level. It occurs in as many as 17 percent of all COVID-19 cases and can lead to respiratory failure and death. Findings presented in a recent review suggest that extracellular superoxide dismutase (EcSOD), a potent antioxidant enzyme produced by the muscles during exercise, can reduce the risk of developing ARDS. A critical feature of the pathogenesis of ARDS is an excessive immune response that leads to increased production of reactiv... exercise covid-19
Read moreRhonda explains NAD+: importance for aging, decline with age, boosters (nicotinamide riboside, nicotinamide mononucleotide), and data in animals and humans. ... aging dna damage genetics resveratrol
Watch now