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    <a data-turbo="false" href="/episodes/how-omega-3s-support-the-aging-brain">
      <h3 class="bold">
        [Podcast] How Omega-3s Support the Aging Brain
      </h3>
</a>    <p>
      Dr. Rhonda Patrick explores omega-3s, brain volume, cognitive function, and the evidence linking DHA to Alzheimer&#39;s risk.
...
          <span class="search-tag">brain</span>
          <span class="search-tag">alzheimer&#39;s</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">omega-3</span>
          <span class="search-tag">inflammation</span>
          <span class="search-tag">rhonda</span>
          <span class="search-tag">autophagy</span>
          <span class="search-tag">cognition</span>
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    <a data-turbo="false" href="/episodes/curcumin-urolithin-a-and-glutamine-what-human-trials-show">
      <h3 class="bold">
        [Podcast] Curcumin, Urolithin A, and Glutamine: What Human Trials Show
      </h3>
</a>    <p>
      Dr. Rhonda Patrick reviews curcumin, urolithin A, and glutamine for inflammation, mitochondria, immunity, and exercise.
...
          <span class="search-tag">aging</span>
          <span class="search-tag">inflammation</span>
          <span class="search-tag">immune system</span>
          <span class="search-tag">mitochondria</span>
          <span class="search-tag">curcumin</span>
          <span class="search-tag">supplements</span>
          <span class="search-tag">urolithin a</span>
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      <h3 class="bold">
        [Podcast] Foods That Support Brain Health With Age
      </h3>
</a>    <p>
      Dr. Rhonda Patrick discusses leafy greens, blueberries, and omega-3s for micronutrients, cognition, mood, and healthy aging.
...
          <span class="search-tag">omega-3</span>
          <span class="search-tag">nutrition</span>
          <span class="search-tag">depression</span>
          <span class="search-tag">cognition</span>
          <span class="search-tag">brain</span>
          <span class="search-tag">magnesium</span>
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      <h3 class="bold">
        [Podcast] How to Cover Common Micronutrient Gaps
      </h3>
</a>    <p>
      Drs. Rhonda Patrick and Mark Hyman discuss vitamin D, omega-3s, multivitamins, magnesium, and sulforaphane for nutrient coverage.
...
          <span class="search-tag">micronutrients</span>
          <span class="search-tag">vitamin d</span>
          <span class="search-tag">omega-3</span>
          <span class="search-tag">magnesium</span>
          <span class="search-tag">sulforaphane</span>
          <span class="search-tag">multivitamin</span>
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        [Story] Heat shock proteins enhance elite cyclists&#39; performance in low-oxygen conditions.
      </h3>
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      During exposure to temperature extremes or hypoxia (low oxygen levels), cells increase their expression of heat shock proteins to stabilize unfolded proteins and repair damaged ones. This phenomenon, referred to as the heat shock response, occurs at the expense of other cellular proteins to protect the cell. Evidence from a 2016 study suggests that the heat shock response enhances athletic performance in low-oxygen environments characteristic of high altitudes. 
The study involved 21 elite cyclists who engaged in ten 60-minute training sessions in either low-oxygen or hot conditions. Before an...
          <span class="search-tag">exercise</span>
          <span class="search-tag">performance</span>
          <span class="search-tag">heat stress</span>
          <span class="search-tag">cold stress</span>
          <span class="search-tag">hypoxia</span>
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        [Story] Resistance training helps cells identify and eliminate abnormal, misfolded proteins.
      </h3>
</a>    <p>
      A new study shows that resistance exercise helps the body&#39;s cells identify and eliminate misfolded proteins – key players in the pathogenesis of many human diseases, including diabetes, atherosclerosis, and neurodegenerative diseases.
The study involved 30 older adults who engaged in an eight-week resistance training program in which they exercised twice a week. Before and after the exercise intervention, researchers measured changes in the number of key proteins in the participants&#39; blood involved in inflammation, aging, and cellular stress responses. 
They also measured levels of IRE1, a pro...
          <span class="search-tag">exercise</span>
          <span class="search-tag">inflammation</span>
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      <h3 class="bold">
        [Story] Diet is superior to drugs and bioactive compounds for metabolic health and longevity.
      </h3>
</a>    <p>
      Nutrient sensing – a cell&#39;s capacity to recognize and respond to fuel sources – plays a critical role in human health, ultimately influencing the aging process and susceptibility to age-related disease. Findings from a recent study suggest that dietary interventions exert powerful effects on proteins produced in the liver, fundamentally &quot;reprogramming&quot; nutrient-sensing pathways.
Multiple studies have investigated the possibility that dietary strategies or drugs can alter nutrient-sensing pathways to improve metabolic health and extend lifespan. For example, robust evidence indicates that inter...
          <span class="search-tag">diet</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">metformin</span>
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        [Story] Macrophages may need lactate and pyruvate for effective nerve regeneration.
      </h3>
</a>    <p>
      Peripheral nerves have the ability to regenerate following trauma, surgery, and exposure to medications and toxins; however, the rate of regeneration is often very slow. The molecular signals that encourage regeneration dissipate over time so that regeneration ends too soon to effectively heal long nerves. Authors of a new report elucidate the role of monocarboxylate transporters and macrophage metabolism is promoting nerve regeneration.
Macrophages (Greek for &quot;large eaters&quot;) are white blood cells that remove pathogens and cellular debris by engulfing and digesting them, making macrophages ess...
          <span class="search-tag">immune system</span>
          <span class="search-tag">lactate</span>
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    <a data-turbo="false" href="/episodes/sleep-dementia-risk">
      <h3 class="bold">
        [Podcast] The Hidden Connection Between Sleep and Dementia
      </h3>
</a>    <p>
      In this short video, Dr. Rhonda Patrick describes one of the mechanisms that drives the beneficial effects of sleep on the brain.
...
          <span class="search-tag">sleep</span>
          <span class="search-tag">brain</span>
          <span class="search-tag">alzheimer&#39;s</span>
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    <a data-turbo="false" href="/stories/5gy8ny">
      <h3 class="bold">
        [Story] Diets rich in nicotinamide riboside (vitamin B3 derivative) protected mice from liver cancer when given carcinogen.
      </h3>
</a>    <p>
      FTA:
&amp;gt; The first mouse model that faithfully reproduces the steps of human HCC development has been developed by researchers. The results of the study indicate that diets rich in nicotinamide riboside, a derivative of vitamin B3, protect these mice from developing HCC in its most initial stage, when genotoxic stress is damaging cellular DNA. They also show a curative effect of the diet in those mice that had previously developed the disease.
...
          <span class="search-tag">nutrition</span>
          <span class="search-tag">cancer</span>
          <span class="search-tag">diet</span>
          <span class="search-tag">vitamin a</span>
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