Diets rich in nicotinamide riboside (vitamin B3 derivative) protected mice from liver cancer when given carcinogen.

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The first mouse model that faithfully reproduces the steps of human HCC development has been developed by researchers. The results of the study indicate that diets rich in nicotinamide riboside, a derivative of vitamin B3, protect these mice from developing HCC in its most initial stage, when genotoxic stress is damaging cellular DNA. They also show a curative effect of the diet in those mice that had previously developed the disease.