Dr. Rhonda Patrick reviews alcohol, nutrients, gut and brain inflammation, conflicting dementia cohorts, APOE4, and evidence limits. ... alcohol brain alzheimer's dementia sleep
Watch now[toc position='left'] Introduction Magnesium is an essential dietary mineral. It plays critical roles in myriad physiological processes, serving as a cofactor to more than 300 enzymes in the human body and maintaining the integrity of cellular structures and DNA. Magnesium deficiency is widespread, affecting more than half of people in the U.S. and increasing the risk of many chronic conditions, including cancer, metabolic disorders, and neurodegenerative diseases. At a glance, magnesium participates in: Enzymatic reactions, serving as a cofactor for more than 300 enzymes involved in variou... magnesium brain nutrition supplements micronutrients
Read moreIn part I of this two-part series on the future of aging research, we discussed the hallmarks of aging and the cutting-edge therapies aimed at understanding ... ... aliquot epigenetics aging stem cells
Listen nowIn this clip, Dr. Axel Montagne discusses how the brain transport of omega-3 DHA may be important for the prevention and possibly as a therapy for dementia. ... brain alzheimer's aging omega-3 dementia
Watch nowRoughly one-quarter of people living in the US carry a genetic variant of the apolipoprotein E gene, called APOE4, the most important genetic risk factor for... ... aliquot brain alzheimer's sleep genetics dementia
Listen now[toc position='left'] Background Vitamin C, also known as ascorbic acid, is an essential nutrient, widely recognized for its antioxidant properties. These properties arise from its potent redox potential due to its capacity to donate electrons to oxidized molecules. Even in small quantities vitamin C can protect critical molecules in the body such as proteins, lipids, carbohydrates, and nucleic acids (DNA and RNA) from damage by reactive oxygen species, which are generated during normal metabolism, by active immune cells, and through exposure to toxins and pollutants (e.g., certain chemotherap... cancer nutrition exercise interesting
Read more[toc position='left'] Nutrition in the first year of life is crucial to an infant's development and lifelong health. Early nutritional deficits are intrinsically linked to impaired mental and physical growth. Consequently, the risk of developing metabolic and cardiovascular diseases such as obesity, diabetes, and hypertension in childhood and later life is likely determined by early feeding and nutritional status. Breastfeeding is the biologically superior way to feed an infant. The American Academy of Pediatrics recommends exclusive breastfeeding for the first six months of an infant's life ... cancer breast cancer circadian rhythm nutrition brain microbiome heart disease diabetes inflammation alcohol stem cells immune system development intelligence
Read more[toc position='left'] Metformin is a drug commonly used to treat type 2 diabetes. It is the fourth most widely prescribed medication in the United States, with more than 80 million prescriptions for the drug written yearly. Metformin is in a class of drugs called biguanides, which impede liver gluconeogenesis (glucose production in the liver), thereby decreasing glucose uptake in the gut and increasing overall glucose utilization by improving insulin sensitivity in skeletal muscle and fat tissue. Multiple studies demonstrate that metformin reduces fasting blood glucose levels by as much as 3.9... exercise aging diabetes
Read more[toc position='left'] Time-restricted eating is a form of daily fasting wherein the time of the day during which a person eats is limited, or compressed. People who practice time-restricted eating typically eat during an 8- to 12-hour daytime window and fast during the remaining 12 to 16 hours. Unlike intermittent fasting, which involves caloric restriction, time-restricted eating permits a person to eat as much as they want during the eating window. Time-restricted eating aligns the eating and fasting cycles to the body’s innate 24-hour circadian system.[ref doi='10.3390/ijms20081911'] Within... fasting diet metabolism sleep circadian rhythm interesting
Read moreDr. Satchin Panda discusses the practical aspects of implementing fasting, time-restricted eating, shift work strategies, and more. ... fasting cancer obesity metabolism diabetes circadian rhythm melatonin time-restricted eating
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