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      <h3 class="bold">
        [Story] Boosting glycogen breakdown in neurons with tau-related damage improves symptoms of neurodegeneration, a potential strategy for Alzheimer&#39;s and related diseases.
      </h3>
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      ...osphate pathway.
These findings suggest that tau-related brain diseases worsen when glycogen builds up in neurons, and that breaking down this excess <span class="text-highlight">sugar</span> protects brain cells. By interrupting what appears to be a vicious cycle between glycogen and tau accumulation, this approach could offer a power...
          <span class="search-tag">alzheimer&#39;s</span>
          <span class="search-tag">blood sugar</span>
          <span class="search-tag">brain</span>
          <span class="search-tag">dementia</span>
          <span class="search-tag">metabolism</span>
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        [Story] Intensive lifestyle changes in prediabetes reduce type 2 diabetes risk by 24% over 20 years, outperforming metformin treatment.
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      ... gained an extra 2.5 diabetes-free years. The most substantial benefits of lifestyle changes were observed among people who started with higher blood <span class="text-highlight">sugar</span> levels, while metformin worked best for younger adults.
These findings suggest that early intervention—especially lifestyle changes—can provide l...
          <span class="search-tag">diabetes</span>
          <span class="search-tag">diet</span>
          <span class="search-tag">exercise</span>
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      <h3 class="bold">
        [Story] A nearly four-decade-long study reveals that maintaining and improving a few key habits from a young age dramatically lowers the risk of cardiovascular disease after age 45.
      </h3>
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      ...-8), which takes into account one&#39;s diet, physical activity, nicotine exposure, sleep, body mass index, blood pressure, cholesterol levels, and blood <span class="text-highlight">sugar</span>. Maintaining high scores across these factors throughout young adulthood can reduce the risk of cardiovascular disease later in life. A recent st...
          <span class="search-tag">aging</span>
          <span class="search-tag">cardiovascular</span>
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        [Topic] Ultra-processed Foods (UPFs)
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      ... daily intake. Unlike whole or minimally processed foods, UPFs are industrial formulations packed with additives, artificial ingredients, and refined <span class="text-highlight">sugar</span>s and fats designed to enhance taste and shelf life—but at a significant cost to health. These foods don&#39;t just contribute to obesity and metaboli...
          <span class="search-tag">brain</span>
          <span class="search-tag">insulin resistance</span>
          <span class="search-tag">fatty liver</span>
          <span class="search-tag">nutrition</span>
          <span class="search-tag">obesity</span>
          <span class="search-tag">metabolism</span>
          <span class="search-tag">diabetes</span>
          <span class="search-tag">micronutrients</span>
          <span class="search-tag">insulin</span>
          <span class="search-tag">metabolic syndrome</span>
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        [Podcast] How to Improve Metabolic Health with HIIT, Circadian-Timed Eating, &amp; Sleep
      </h3>
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      Dr. Rhonda Patrick explains how HIIT, circadian-timed eating, and quality sleep improve metabolic health and reduce chronic disease risk.
...
          <span class="search-tag">metabolism</span>
          <span class="search-tag">exercise</span>
          <span class="search-tag">sleep</span>
          <span class="search-tag">time-restricted eating</span>
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        [Story] Kombucha reduces blood glucose levels by nearly 30 percent.
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      ...Kombucha is a fermented beverage made from tea, <span class="text-highlight">sugar</span>, bacteria, and yeast. Some evidence suggests that kombucha exerts antimicrobial, antioxidant, detoxifying, and liver-protective effects (https://...
          <span class="search-tag">nutrition</span>
          <span class="search-tag">gut</span>
          <span class="search-tag">diet</span>
          <span class="search-tag">microbiome</span>
          <span class="search-tag">diabetes</span>
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        [Story] Omega-3s improve metabolic markers in women with gestational diabetes.
      </h3>
</a>    <p>
      ...67058.2018.1526916), which found that compared to women who took a placebo, those who took supplemental omega-3s had considerably lower fasting blood <span class="text-highlight">sugar</span> levels and insulin resistance. Learn about other health benefits associated with omega-3s in our comprehensive overview article. (https://www.fou...
          <span class="search-tag">diabetes</span>
          <span class="search-tag">insulin resistance</span>
          <span class="search-tag">omega-3</span>
          <span class="search-tag">inflammation</span>
          <span class="search-tag">pregnancy</span>
          <span class="search-tag">insulin</span>
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      <h3 class="bold">
        [Topic] Hallmarks of aging
      </h3>
</a>    <p>
      ...15548627.2020.1846302&#39;]
Deregulated nutrient sensing
The body employs many sensing pathways that detect intra- and extracellular fat, amino acid, and <span class="text-highlight">sugar</span> concentrations. During periods of food abundance, these pathways facilitate growth and storage, whereas during periods of scarcity, they trigger ...
          <span class="search-tag">mitochondria</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">omega-3</span>
          <span class="search-tag">stem cells</span>
          <span class="search-tag">aerobic</span>
          <span class="search-tag">senescence</span>
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      <h3 class="bold">
        [Story] Time-restricted feeding reduces weight gain and cholesterol in male mice.
      </h3>
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      ...A Western diet pattern, characterized by a low intake of fruits and vegetables and a high intake of <span class="text-highlight">sugar</span> and processed foods, promotes the development of obesity and metabolic disease. Time restricted eating has been shown to decrease weight and impr...
          <span class="search-tag">cholesterol</span>
          <span class="search-tag">fasting</span>
          <span class="search-tag">fat</span>
          <span class="search-tag">muscle</span>
          <span class="search-tag">sugar</span>
          <span class="search-tag">time-restricted eating</span>
          <span class="search-tag">weight loss</span>
          <span class="search-tag">lipopolysaccharide</span>
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      <h3 class="bold">
        [Topic] Neu5Gc
      </h3>
</a>    <p>
      ...[toc position=&#39;left&#39;]
N-glycolylneuraminic acid, or Neu5Gc, is a sialic acid – a nine-carbon <span class="text-highlight">sugar</span> molecule – produced by most nonhuman mammals. Sialic acids serve diverse roles, such as mediating cell-to-cell interactions, triggering cell sign...
          <span class="search-tag">diet</span>
          <span class="search-tag">nutrition</span>
          <span class="search-tag">cancer</span>
          <span class="search-tag">inflammation</span>
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