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        [Topic] Biological Age Clocks
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Biological aging clocks are among the most important tools in modern longevity science. They attempt to answer a deceptively simple question: can we measure how fast a person is aging biologically, rather than just counting the number of years they have been alive?
The answer is yes—but with important caveats.
Epigenetic clocks use patterns of DNA methylation, a chemical tagging system on DNA, to estimate different aspects of aging. Some clocks estimate chronological age. Others predict disease risk, mortality risk, or the current pace of biological aging. This means biol...
          <span class="search-tag">epigenetics</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">telomeres</span>
          <span class="search-tag">genetics</span>
          <span class="search-tag">stem cells</span>
          <span class="search-tag">omega-3</span>
          <span class="search-tag">dna damage</span>
          <span class="search-tag">biomarkers</span>
          <span class="search-tag">vitamin d</span>
          <span class="search-tag">senescence</span>
          <span class="search-tag">multivitamin</span>
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        [Topic] Creatine and Cardioprotection
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Creatine (https://www.foundmyfitness.com/topics/creatine) is a naturally occurring compound that is critical in storing and releasing cellular energy. It also participates in many biological processes driving pregnancy outcomes, maintaining bone mineral density and muscle mass in older adults, improving neurological function, and aiding the immune system to fight cancer. Creatine is best known for its widespread use as a dietary supplement to enhance physical performance.
Creatine, phosphocreatine, creatine transporters, and creatine kinase enzymes are expressed in the en...
          <span class="search-tag">cardiovascular</span>
          <span class="search-tag">heart disease</span>
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        [Podcast] Q&amp;A #66: GLP-1 Agonists Beyond Weight Loss—Brain, Heart, Addiction, &amp; Muscle Preservation
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      Dr. Rhonda Patrick discusses GLP-1 agonists, alpha-lipoic acid, ubiquinone vs. ubiquinol, calcium needs, and liquid biopsy cancer screening.
...
          <span class="search-tag">rhonda</span>
          <span class="search-tag">cancer</span>
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          <span class="search-tag">calcium</span>
          <span class="search-tag">dental</span>
          <span class="search-tag">weight loss</span>
          <span class="search-tag">Microplastics</span>
          <span class="search-tag">GLP-1</span>
          <span class="search-tag">Ubiquinol</span>
          <span class="search-tag">pollution</span>
          <span class="search-tag">PFAS</span>
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        [Podcast] Factors that accelerate or slow epigenetic aging | Dr. Morgan Levine
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      In this clip, Drs. Levine and Patrick discuss genetic and environmental factors that can accelerate or slow epigenetic aging.
...
          <span class="search-tag">epigenetics</span>
          <span class="search-tag">cancer</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">diabetes</span>
          <span class="search-tag">inflammation</span>
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        [Topic] Aerobic exercise
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Aerobic exercise can be defined as physical activity that increases aerobic metabolism, meaning energy-generating processes that require oxygen. Common examples of aerobic exercises are walking, running, swimming, dancing, and other activities that increase heart rate and breathing. Exercise elicits a wide range of physiological changes in the body that improve cardiovascular, neurological, and metabolic health. 
Current physical activity guidelines from the United States Department of Health and Human Services (https://health.gov/our-work/nutrition-physical-activity/phys...
          <span class="search-tag">depression</span>
          <span class="search-tag">exercise</span>
          <span class="search-tag">brain</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">heart disease</span>
          <span class="search-tag">aerobic</span>
          <span class="search-tag">bdnf</span>
          <span class="search-tag">interesting</span>
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    <a data-turbo="false" href="/episodes/aliquot-23-slow-epigenetic-clock">
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        [Podcast] Aliquot #23: Altering the rate of your epigenetic clock
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      Recent discoveries in the field of epigenetics suggest we might be able to slow aging, based on the realization that not everyone ages at the same rate. Evid...
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          <span class="search-tag">aliquot</span>
          <span class="search-tag">diet</span>
          <span class="search-tag">epigenetics</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">biomarkers</span>
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        [Podcast] Aliquot #17: Time restricted eating for better metabolic health, part 2
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      Circadian rhythms modulate a wide array of the body&#39;s physiological processes, ultimately influencing body weight, performance, and susceptibility to disease...
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          <span class="search-tag">aliquot</span>
          <span class="search-tag">metabolism</span>
          <span class="search-tag">insulin resistance</span>
          <span class="search-tag">fasting</span>
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          <span class="search-tag">time-restricted eating</span>
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        [Topic] Vitamin D
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Introduction
Vitamin D is a fat-soluble vitamin that is stored in the liver and fatty tissues of the body. Perhaps best known for its role in maintaining calcium balance and bone health, vitamin D is critical in many physiological processes, such as blood pressure regulation, immune function, and cell growth. Poor vitamin D status is implicated in the pathogenesis of many acute and chronic diseases, including rickets, osteoporosis, multiple sclerosis, and cancer. 
Vitamin D is a controversial topic in the scientific community and has contributed to much debate regarding t...
          <span class="search-tag">gut</span>
          <span class="search-tag">blood pressure</span>
          <span class="search-tag">vitamin d</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">vitamin k</span>
          <span class="search-tag">calcium</span>
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        [Topic] Quercetin
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Background
Quercetin is a bioactive compound that exerts antioxidant and anti-inflammatory properties.[ref pmid=&#39;26393898&#39;] Research indicates that quercetin may alleviate chronic health conditions such as hypertension, neurodegenerative disease, arthritis, and lung and kidney diseases and may be beneficial in combating aging-related diseases. Although much of the quercetin research has been performed in animals, some clinical trials have been conducted, and others are ongoing. 
A naturally occurring member of the flavonoid class of plant polyphenol (https://www.foundmyfi...
          <span class="search-tag">aging</span>
          <span class="search-tag">antioxidant</span>
          <span class="search-tag">nutrition</span>
          <span class="search-tag">inflammation</span>
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        [Topic] Vitamin C
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Background
Vitamin C, also known as ascorbic acid, is an essential nutrient, widely recognized for its antioxidant properties. These properties arise from its potent redox potential due to its capacity to donate electrons to oxidized molecules. Even in small quantities vitamin C can protect critical molecules in the body such as proteins, lipids, carbohydrates, and nucleic acids (DNA and RNA) from damage by reactive oxygen species, which are generated during normal metabolism, by active immune cells, and through exposure to toxins and pollutants (e.g., certain chemotherap...
          <span class="search-tag">cancer</span>
          <span class="search-tag">nutrition</span>
          <span class="search-tag">exercise</span>
          <span class="search-tag">interesting</span>
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