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    <a data-turbo="false" href="/episodes/aliquot-104-science-optimizing-sleep">
      <h3 class="bold">
        [Podcast] Aliquot #104: The Science of Optimizing Sleep
      </h3>
</a>    <p>
      Adequate, quality sleep is essential for the body&#39;s recovery and repair, promoting optimal physical and mental health. Getting a good night&#39;s sleep can be ch...
...
          <span class="search-tag">aliquot</span>
          <span class="search-tag">sleep</span>
          <span class="search-tag">circadian rhythm</span>
          <span class="search-tag">tissue repair</span>
          <span class="search-tag">mental health</span>
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    <a data-turbo="false" href="/episodes/intestinal-permeability">
      <h3 class="bold">
        [Podcast] Intestinal Permeability: the Bacterial link to Aging, Brain Barrier Dysfunction &amp; Metabolic Disorder
      </h3>
</a>    <p>
      Dr. Patrick&#39;s keynote: compromised intestinal barrier affects human health—cardiometabolic function, neurological health, behavior, and more.
...
          <span class="search-tag">intestinal permeability</span>
          <span class="search-tag">alzheimer&#39;s</span>
          <span class="search-tag">gut</span>
          <span class="search-tag">heart disease</span>
          <span class="search-tag">inflammation</span>
          <span class="search-tag">depression</span>
          <span class="search-tag">blood-brain barrier</span>
          <span class="search-tag">lipopolysaccharide</span>
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      <h3 class="bold">
        [Topic] Hallmarks of aging
      </h3>
</a>    <p>
      [toc position=&#39;left&#39;]
Aging refers to the collective physiological, functional, and mental changes that accrue in a biological organism over time. The hallmarks of aging are observable biological patterns of dysfunction that occur with aging. Integral to the aging process is inflammaging, the chronic, low-grade inflammation that occurs with aging.[ref doi=&#39;10.1111/j.1749-6632.2000.tb06651.x&#39;] The mechanisms that drive inflammaging and the pathological conditions that arise because of it are bidirectional and involve multiple physiological processes and pathways, many of which directly or indir...
          <span class="search-tag">mitochondria</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">omega-3</span>
          <span class="search-tag">stem cells</span>
          <span class="search-tag">aerobic</span>
          <span class="search-tag">senescence</span>
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      <h3 class="bold">
        [Podcast] Q&amp;A #18: How to Test Blood Lipids—and Which Magnesium Form Is Best?
      </h3>
</a>    <p>
      Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&amp;amp;A session.
...
          <span class="search-tag">rhonda</span>
          <span class="search-tag">exercise</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">sleep</span>
          <span class="search-tag">telomeres</span>
          <span class="search-tag">vitamin c</span>
          <span class="search-tag">cholesterol</span>
          <span class="search-tag">omega-3</span>
          <span class="search-tag">dna damage</span>
          <span class="search-tag">fasting</span>
          <span class="search-tag">coffee</span>
          <span class="search-tag">magnesium</span>
          <span class="search-tag">eyes</span>
          <span class="search-tag">calcium</span>
          <span class="search-tag">time-restricted eating</span>
          <span class="search-tag">breast milk</span>
          <span class="search-tag">moringa</span>
          <span class="search-tag">lactate</span>
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        [Topic] Hydrolyzed collagen 
      </h3>
</a>    <p>
      [toc position=&#39;left&#39;]
Background
Collagens are major structural proteins in numerous body tissues, including tendons, ligaments, cartilage, skin, blood vessels, muscles, gut tissue, and dentin.[ref doi=&#39;10.1101/cshperspect.a004978&#39;] They are the most abundant proteins in the body, comprising 30 percent of the total protein mass. The human body continuously manufactures collagens to maintain tissue structural integrity. However, aging drives a progressive decrease in protein synthesis and reduced capacity to produce new collagen.[ref doi=&#39;10.1016/S0047-6374(01)00337-2&#39;]
Collagens are also highl...
          <span class="search-tag">interesting</span>
          <span class="search-tag">nutrition</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">metabolism</span>
          <span class="search-tag">autoimmunity</span>
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      <h3 class="bold">
        [Podcast] Q&amp;A #6: Fasting, Omega-3s, &amp; Continuous Glucose Monitoring
      </h3>
</a>    <p>
      Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&amp;amp;A session.
...
          <span class="search-tag">rhonda</span>
          <span class="search-tag">vitamin d</span>
          <span class="search-tag">exercise</span>
          <span class="search-tag">sleep</span>
          <span class="search-tag">omega-3</span>
          <span class="search-tag">fasting</span>
          <span class="search-tag">pregnancy</span>
          <span class="search-tag">adhd</span>
          <span class="search-tag">muscle</span>
          <span class="search-tag">autophagy</span>
          <span class="search-tag">resveratrol</span>
          <span class="search-tag">sulforaphane</span>
          <span class="search-tag">metformin</span>
          <span class="search-tag">supplements</span>
          <span class="search-tag">ketogenic diet</span>
          <span class="search-tag">wearable technology</span>
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        [Topic] Nicotinamide riboside
      </h3>
</a>    <p>
      [toc position=&#39;left&#39;]
Nicotinamide riboside (NR) is a precursor molecule for the biosynthesis of nicotinamide adenine dinucleotide, or NAD+, a coenzyme that participates in the production of cellular energy and repair. Two other NAD+ precursors, nicotinic acid (NA) and nicotinamide (NAM, also called niacinamide), along with nicotinamide riboside, are often collectively referred to as niacin (vitamin B3) or niacin equivalents. These precursors are not equally allocated throughout the body, exhibiting preferential distribution among the blood, brain, gut, and other organs. NAD+ can also be produ...
          <span class="search-tag">obesity</span>
          <span class="search-tag">nad+</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">breast milk</span>
          <span class="search-tag">cardiovascular</span>
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        [Topic] Depression
      </h3>
</a>    <p>
      [toc position=&#39;left&#39;]
Depression is a neuropsychiatric disorder characterized by negative mood, loss of interest in doing things, and metabolic, hormonal, and immune disturbances that can degrade a person&#39;s quality of life and increase their risk of disease and death. The World Health Organization estimates that approximately 322 million people – more than 4 percent of the global population – currently live with depression,[ref doi=&#39;10.1001/jama.2017.3826&#39;] the most common mental health disorder worldwide. Between 2005 and 2015 (the most recent years for which robust meta-analyses are availabl...
          <span class="search-tag">inflammation</span>
          <span class="search-tag">probiotics</span>
          <span class="search-tag">circadian rhythm</span>
          <span class="search-tag">meditation</span>
          <span class="search-tag">behavior</span>
          <span class="search-tag">heat stress</span>
          <span class="search-tag">depression</span>
          <span class="search-tag">metabolism</span>
          <span class="search-tag">neurotransmitter</span>
          <span class="search-tag">nutrition</span>
          <span class="search-tag">exercise</span>
          <span class="search-tag">brain</span>
          <span class="search-tag">microbiome</span>
          <span class="search-tag">interesting</span>
          <span class="search-tag">omega-3</span>
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    <a data-turbo="false" href="/episodes/orthomolecular-congress-bussum-2015">
      <h3 class="bold">
        [Podcast] PRESENTATION: Rhonda Speaks at the Orthomolecular Congress in Bussum, Netherlands
      </h3>
</a>    <p>
      Dr. Patrick&#39;s keynote lecture at MBOG Congres 2015 in the Netherlands covers micronutrient inadequacy and Dr. Bruce Ames&#39; triage theory.
...
          <span class="search-tag">nutrition</span>
          <span class="search-tag">vitamin d</span>
          <span class="search-tag">diet</span>
          <span class="search-tag">obesity</span>
          <span class="search-tag">aging</span>
          <span class="search-tag">omega-3</span>
          <span class="search-tag">inflammation</span>
          <span class="search-tag">depression</span>
          <span class="search-tag">dna damage</span>
          <span class="search-tag">behavior</span>
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      <h3 class="bold">
        [Podcast] Jim Kean Talks Biomarkers, Building a Spectator Sport
      </h3>
</a>    <p>
      Jim Kean is the CEO of National Pro Grid League (NPGL) and founder of WellnessFX.
...
          <span class="search-tag">biomarkers</span>
          <span class="search-tag">vitamin d</span>
          <span class="search-tag">nutrition</span>
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          <span class="search-tag">alzheimer&#39;s</span>
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          <span class="search-tag">microbiome</span>
          <span class="search-tag">performance</span>
          <span class="search-tag">insulin resistance</span>
          <span class="search-tag">podcast</span>
          <span class="search-tag">cholesterol</span>
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