Dr. Rhonda Patrick and Dr. Charles Brenner discuss NAD precursors, NR versus NMN, NAD IV drips, and what truly boosts NAD for recovery and longevity. ... nad+ pregnancy dna damage aging resveratrol oxidative stress
Watch now[toc position='left'] This post originally went out to subscribers to the FoundMyFitness newsletter. Sign up here to start receiving it! (https://www.foundmyfitness.com/newsletter) Protein is still (somehow) controversial. Should we restrict protein in favor of longevity and reducing cancer risk, or should we maximize our intake in favor of building muscle mass and enhancing performance? The answer lies somewhere in the middle. But one thing is for certain—the current recommendations don't accurately reflect the scientific evidence. That's why I sat down with Dr. Peter Attia as a guest on his ... aging cancer muscle strength protein exercise
Read more[toc position='left'] The blood-brain barrier comprises various membranes that separate the central nervous system (CNS) and the peripheral circulatory system. The purpose of this barrier is to allow the passage of nutrients and cell signals from the bloodstream to nerves and supporting cells in the CNS while excluding harmful substances. Genetic predispositions, environmental exposures, and aging may weaken the integrity of this barrier, allowing endotoxins and inflammatory immune cells to infiltrate the brain, contributing to accelerated brain aging and the risk of neurodegenerative diseases... omega-3 immune system blood-brain barrier brain alzheimer's gut obesity
Read more[toc position='left'] Aging refers to the collective physiological, functional, and mental changes that accrue in a biological organism over time. The hallmarks of aging are observable biological patterns of dysfunction that occur with aging. Integral to the aging process is inflammaging, the chronic, low-grade inflammation that occurs with aging.[ref doi='10.1111/j.1749-6632.2000.tb06651.x'] The mechanisms that drive inflammaging and the pathological conditions that arise because of it are bidirectional and involve multiple physiological processes and pathways, many of which directly or indir... mitochondria aging omega-3 stem cells aerobic senescence
Read more[toc position='left'] Introduction Vitamin D is a fat-soluble vitamin that is stored in the liver and fatty tissues of the body. Perhaps best known for its role in maintaining calcium balance and bone health, vitamin D is critical in many physiological processes, such as blood pressure regulation, immune function, and cell growth. Poor vitamin D status is implicated in the pathogenesis of many acute and chronic diseases, including rickets, osteoporosis, multiple sclerosis, and cancer. Vitamin D is a controversial topic in the scientific community and has contributed to much debate regarding t... gut blood pressure vitamin d aging vitamin k calcium
Read more[toc position='left'] Background Berberine is an alkaloid compound present in the roots, stems, rhizomes, and bark of a variety of plants, including Californian poppy, goldenseal, cork tree, Chinese goldthread, Oregon grape, and several plants in the Berberis genus. It is also widely available as a dietary supplement. Berberine has a long history of use in the ancient and traditional medicine systems of India, China, and Persia. Research demonstrates that berberine may exert pharmacological effects against certain chronic health conditions such as cardiovascular disease, gastrointestinal disor... exercise brain parkinson's depression aging diabetes heart disease fatty liver
Read moreIrritable bowel syndrome (IBS), an intestinal disorder characterized by abdominal pain, bloating, and alternating episodes of diarrhea and constipation, affects as many as 14 percent of people living in the United States. Evidence suggests that people with IBS often have dysbiosis, an imbalance in the microbial makeup of the gut. A recent study indicates that human milk oligosaccharides may be beneficial in modulating the gut microbial profile of people who have IBS. Human milk oligosaccharides (HMOs) are complex, indigestible sugars in breast milk. They serve as prebiotics – compounds that i... gut
Read moreMaintaining a healthy weight requires balancing energy intake with expenditure. A variety of elements influence how physically active we are, including genetic, cultural, and environmental factors. Evidence from a new study suggests that epigenetic changes in agouti-related proteins may regulate voluntary exercise behavior in mice. Agouti-related proteins are neuropeptides produced primarily in the hypothalamus. They regulate appetite, metabolism, and energy expenditure. Epigenetic changes are biological mechanisms that regulate gene expression (how and when certain genes are turned on or of... exercise epigenetics protein
Read moreThe sugar is known as human milk oligosaccharides (HMO's), which have previously been shown to feed beneficial bacteria in the infant's gut. The HMO's have now been shown to sensitize target bacteria including Strep B (which many pregnant women test positive for) and then they kill them. ... microbiome prebiotics microbes
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