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      <h3 class="bold">
        [Podcast] Q&amp;A #74: How to Slow Immune Aging—Plus Gluten, Stroke Risk, &amp; APOE4
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      Dr. Rhonda Patrick discusses stroke risk, eczema, immune resilience, her new smoothie recipe, and whether everyone should cut out gluten.
...
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          <span class="search-tag">immune system</span>
          <span class="search-tag">cholesterol</span>
          <span class="search-tag">gluten</span>
          <span class="search-tag">sauna</span>
          <span class="search-tag">stroke</span>
          <span class="search-tag">intestinal permeability</span>
          <span class="search-tag">microbiome</span>
          <span class="search-tag">green tea</span>
          <span class="search-tag">L-Theanine</span>
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        [Topic] Coffee
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Coffee is more than just a morning ritual or a comforting pick-me-up—it&#39;s a scientifically supported pathway to improved health, performance, and longevity. As one of the world&#39;s most widely consumed beverages, coffee has long been celebrated for its energizing properties. However, emerging research now highlights its remarkable potential to extend lifespan, slow biological aging, and reduce the risk of chronic diseases like heart disease, diabetes, and certain cancers.
Coffee reduces the body&#39;s biological age by modulating gene expression and protects against cardiovascular events and n...
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        [Podcast] How To Use Coffee To Live Longer (Full Guide &amp; Research)
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      Dr. Rhonda Patrick discusses coffee&#39;s remarkable ability to slow biological aging, reduce DNA damage, and lower cancer risk. 
...
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        [Topic] Alcohol
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Alcohol is one of the most heavily used and abused drugs. It&#39;s also a very controversial topic, in part because alcohol plays such a large role in societies and cultures around the world. For many, it&#39;s a normal part of daily life.
There is also a lot of confusion about alcohol. There&#39;s no doubt that alcohol can have a personal and public health impact. On the other hand, research in the last few decades suggests that not only may a moderate intake of alcohol not be harmful, but it might also be protective against certain diseases. This idea is heavily debated, and conflicting evidence h...
          <span class="search-tag">cancer</span>
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        [Podcast] The Truth About Alcohol: Risks, Benefits, and Everything In-Between | Dr. Rhonda Patrick
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</a>    <p>
      In this episode, we’re taking a deep dive into alcohol. We’ll explore the science, misconceptions, controversies, and health effects of this widely used drug.
...
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          <span class="search-tag">sleep</span>
          <span class="search-tag">heart disease</span>
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        [Podcast] Q&amp;A #48: Are Sunflower Oil and Soy Foods Harmful?—Plus Restoring Gut Health After Antibiotics
      </h3>
</a>    <p>
      Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&amp;amp;A session.
...
          <span class="search-tag">rhonda</span>
          <span class="search-tag">gut</span>
          <span class="search-tag">microbiome</span>
          <span class="search-tag">estrogen</span>
          <span class="search-tag">caffeine</span>
          <span class="search-tag">allergies</span>
          <span class="search-tag">dental</span>
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          <span class="search-tag">supplements</span>
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        [Topic] Toll-like receptors
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Toll-like receptors are a family of pattern recognition receptors expressed on the surface of immune and other cells. Toll-like receptors are the principal inducers of innate immunity[ref doi=&#39;10.1186/cc1471&#39;], activating transcription factors such as NF-kB that increase the expression of inflammatory cytokines. Among toll-like receptors, TLR4 is notable for recognizing lipopolysaccharide (LPS), a structure found on the outer membranes of Gram-negative bacteria. This overview will predominantly focus on TLR4 and its involvement in human health, disease, and behavior.
Toll...
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        [Podcast] Aliquot #53: Intestinal permeability
      </h3>
</a>    <p>
      A healthy intestinal barrier limits the transport of pathogens and endotoxins from the gut to the bloodstream; however, increased gut permeability (known as ...
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        [Topic] Intestinal permeability
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      [toc position=&#39;left&#39;]
A single layer of epithelial cells lines the entire digestive tract, facilitating the exchange of nutrients between the intestine and the bloodstream. This layer, referred to as the intestinal epithelium, must be permeable to nutrients yet impermeable to pathogens. 
[tweetbox text=&#39;&quot;Increased intestinal permeability (also known as &quot;leaky gut&quot;) allows pathogens to leak through the intestinal barrier and pass directly into the bloodstream, promoting inflammation.&quot;&#39; tweet=&#39;&quot;Increased intestinal permeability (also known as &quot;leaky gut&quot;) allows pathogens to leak through the int...
          <span class="search-tag">intestinal permeability</span>
          <span class="search-tag">butyrate</span>
          <span class="search-tag">gut</span>
          <span class="search-tag">microbiome</span>
          <span class="search-tag">polyphenol</span>
          <span class="search-tag">autoimmunity</span>
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        [Topic] Brain-derived neurotrophic factor (BDNF)
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Brain-derived neurotrophic factor, or BDNF, is a growth factor relevant to aging, brain function, behavior, metabolism, energy expenditure, and satiety. BDNF serves as a cell signaling protein, plays vital roles in numerous signaling pathways associated with a variety of disorders ranging from depression, (https://www.foundmyfitness.com/topics/depression) schizophrenia, and addiction to obesity and diabetes, and may serve as a hormone. It is perhaps best known for its influence on the formation, growth, survival, and development of neurons and for its role in mediating th...
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          <span class="search-tag">interesting</span>
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