Derek reviews how nutrient status and selected supplements may influence testosterone, with effects that vary by baseline status. ... vitamin d hormones magnesium rhonda testosterone zinc supplements
Watch nowDr. Ben Bikman and Rhonda Patrick discuss the primary causes of insulin resistance and how to reverse it in as little as 90 days. ... insulin resistance insulin blood sugar diabetes saturated fat diet nutrition
Watch now[toc] Alcohol is one of the most heavily used and abused drugs. It's also a very controversial topic, in part because alcohol plays such a large role in societies and cultures around the world. For many, it's a normal part of daily life. There is also a lot of confusion about alcohol. There's no doubt that alcohol can have a personal and public health impact. On the other hand, research in the last few decades suggests that not only may a moderate intake of alcohol not be harmful, but it might also be protective against certain diseases. This idea is heavily debated, and conflicting evidence h... cancer cardiovascular alcohol brain alzheimer's diabetes breast cancer
Read moreMicroplastics are ubiquitous in everyday life. This episode details how they impact our health and ways that we can limit our exposure. ... pollution Microplastics brain pregnancy bisphenol a environment neurodegeneration reproductive health PFAS
Watch nowIn this episode, we’re taking a deep dive into alcohol. We’ll explore the science, misconceptions, controversies, and health effects of this widely used drug. ... alcohol exercise brain alzheimer's cancer aging microbiome sleep heart disease
Watch nowSugar substitutes are food products or additives that provide the sweet taste of sugar, without the calories. Evidence suggests that sugar substitutes have s... ... aliquot diet microbiome metabolism sugar
Listen now[toc position='left'] The blood-brain barrier comprises various membranes that separate the central nervous system (CNS) and the peripheral circulatory system. The purpose of this barrier is to allow the passage of nutrients and cell signals from the bloodstream to nerves and supporting cells in the CNS while excluding harmful substances. Genetic predispositions, environmental exposures, and aging may weaken the integrity of this barrier, allowing endotoxins and inflammatory immune cells to infiltrate the brain, contributing to accelerated brain aging and the risk of neurodegenerative diseases... omega-3 immune system blood-brain barrier brain alzheimer's gut obesity
Read more[toc position='left'] Toll-like receptors are a family of pattern recognition receptors expressed on the surface of immune and other cells. Toll-like receptors are the principal inducers of innate immunity[ref doi='10.1186/cc1471'], activating transcription factors such as NF-kB that increase the expression of inflammatory cytokines. Among toll-like receptors, TLR4 is notable for recognizing lipopolysaccharide (LPS), a structure found on the outer membranes of Gram-negative bacteria. This overview will predominantly focus on TLR4 and its involvement in human health, disease, and behavior. Toll... toll-like receptors gut aging microbiome inflammation immune system intestinal permeability omega-3 endotoxemia
Read more[toc position='left'] Background Zinc is an essential nutrient that participates in numerous biological processes and modulates the activity of more than 300 enzymes and 2,000 transcription factors.[ref doi='10.1136/bmj.326.7386.409'] First identified for its influence on growth and development, zinc is now understood to play critical roles in immune function, protein synthesis, wound healing, DNA synthesis, and cell division. History The importance of zinc in the human diet first became apparent in the early 1960s, after a patient with a rare syndrome presented to Dr. Ananda Prasad, a physic... nutrition interesting zinc
Read more[toc position='left'] Introduction [tweetbox text='"Modulation of autophagy may represent a promising therapeutic approach for extending human lifespan and healthspan."' tweet='"Modulation of autophagy may represent a promising therapeutic approach for extending human lifespan and healthspan." https://www.foundmyfitness.com/topics/autophagy'] Homeostasis, a cell's ability to maintain a constant internal environment, is essential to cell survival. It is predicated on achieving an equilibrium between the production and degradation of cellular components. One major pathway for degradation is auto... aging mitochondria autophagy nutrition exercise parkinson's cancer autoimmunity
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