[toc position='left'] Biological aging clocks are among the most important tools in modern longevity science. They attempt to answer a deceptively simple question: can we measure how fast a person is aging biologically, rather than just counting the number of years they have been alive? The answer is yes—but with important caveats. Epigenetic clocks use patterns of DNA methylation, a chemical tagging system on DNA, to estimate different aspects of aging. Some clocks estimate chronological age. Others predict disease risk, mortality risk, or the current pace of biological aging. This means biol... epigenetics aging telomeres genetics stem cells omega-3 dna damage biomarkers vitamin d senescence multivitamin
Read more[toc position='left'] Toll-like receptors are a family of pattern recognition receptors expressed on the surface of immune and other cells. Toll-like receptors are the principal inducers of innate immunity[ref doi='10.1186/cc1471'], activating transcription factors such as NF-kB that increase the expression of inflammatory cytokines. Among toll-like receptors, TLR4 is notable for recognizing lipopolysaccharide (LPS), a structure found on the outer membranes of Gram-negative bacteria. This overview will predominantly focus on TLR4 and its involvement in human health, disease, and behavior. Toll... toll-like receptors gut aging microbiome inflammation immune system intestinal permeability omega-3 endotoxemia
Read moreSmall changes can make big differences in how long and how well we live. Diet stands out as low-hanging fruit for influencing our lifespan. Optimizing macron... ... aliquot nutrition diet aging mortality time-restricted eating
Listen nowDr. Rhonda Patrick and MedCram founders Dr. Roger Seheult and physician assistant Kyle Allred discuss COVID-19 vaccines. ... covid-19 heart disease inflammation immune system vaccine
Watch nowDr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session. ... rhonda vitamin d microbiome sleep vitamin c immune system sauna covid-19 supplements
Watch now[toc position='left'] Creatine is a naturally occurring compound that is critical in storing and releasing cellular energy. It also participates in many biological processes driving pregnancy outcomes, maintaining bone mineral density and muscle mass in older adults, improving neurological function, and aiding the immune system to fight cancer. Creatine is best known for its widespread use as a dietary supplement to enhance physical performance. Creatine uptake, synthesis, storage, and supplementation Creatine uptake Creatine can be supplied exogenously (from dietary or supplemental sources) ... metabolism neurodegeneration nutrition brain aging depression pregnancy
Read more[toc position='left'] Salmon roe – sometimes referred to as "salmon caviar" – is the internal egg mass found in female salmon. It is served in a variety of dishes, including sushi and pasta, or as a garnish or condiment to seafood or eggs. Salmon roe is rich in protein, vitamins, astaxanthin, and the omega-3 fatty acids eicosapentaenoic acid, or EPA, and docosahexaenoic acid, or DHA. Omega-3 fatty acids are long-chain polyunsaturated fatty acids. They are considered essential fatty acids because the human body cannot make them. Alpha-linolenic acid, or ALA, an omega-3 fatty acid that serves a... brain aging omega-3 diet mental health dementia alzheimer's
Read moreDr. Gordon Lithgow discusses the roles of protein aggregation, iron overload, and others in the aging process. ... aging vitamin d parkinson's podcast heat stress curcumin video
Watch nowDr. Satchin Panda discusses the roles that fasting, time-restricted eating, and circadian rhythms play in human health. ... fasting obesity podcast circadian rhythm melatonin video fatty liver time-restricted eating
Watch nowDr. Rhonda Patrick explains cold shock as hormesis, a beneficial stressor that triggers adaptive processes, promoting resilience. ... cold stress exercise brain cancer obesity performance inflammation immune system mental health muscle
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