High dose cannabidiol, a non-psychoactive compound found in cannabis, inhibits the motivation to consume methamphetamine in rats. This suggests high dose cannabidiol may have the potential to help treat methamphetamine addiction.

This was an animal study where rats were given a pretty high dose of cannabidiol, 80mg per kg body weight which translates to 12.8 mg/kg in humans. Lower doses did not have an effect on methamphetamine addiction in rats. Clinical studies are still needed to confirm but this preclinical evidence seems promising.