Dr. Axel Montagne studies how, when, and where the blood-brain barrier becomes dysfunctional preceding dementia and in the earliest stages of age-related cognitive decline.

Dr. Brad Schoenfeld is a professor at Lehman College, CUNY, in the Bronx, New York.

When people exercise as part of a treatment for alcohol abuse disorder it reduces their volume of alcohol consumption. But why? One reason may be FGF21.

In this episode, George Church, Ph.D., one of the world's leading geneticists, discusses his work on how revolutionary technologies such as multiplex genome editing and genome writing could advance human health.

Lifestyle factors and new technologies offer the promise of living longer, healthier lives, but is there a limit to the human lifespan? This episode explores the different theories supporting this hotly debated topic.

In this episode, Dr. Stuart Phillips discusses the roles exercise and nutrition play in influencing human skeletal muscle protein turnover and highlights the importance of maintaining muscle mass and strength throughout the lifespan.

In this keynote address, Dr. Rhonda Patrick describes how the loss of health and integrity of the intestinal barrier influences multiple aspects of human health – including cardiometabolic function, neurological health, behavior, and more.

In this episode, Dr. Dominic D'Agostino, a world-class researcher and ketogenic diet practitioner, discusses how ketones affect exercise performance, reduce inflammation, and improve neurological health.

This episode features a discussion with MedCram co-founder Kyle Allred about all things sauna. From sauna's use as an exercise mimetic to its anti-inflammatory, mood-elevating, and detoxifying properties.

Morgan Levine, Ph.D., is a founding principal investigator at Altos Labs and an assistant professor of pathology at the Yale University School of Medicine.

In response to cold-water immersion, the body increases circulation of norepinephrine. This physiological response sets off a cascade of adaptive effects that affect metabolism, the brain, and genetic expression.

Peter Diamandis, MD and Tony Robbins are entrepreneurs and authors of "Life Force," a book on precision medicine and health technology.

The work on Eran Elinav, MD, PhD focuses on understanding the complex interactions between humans and the bacteria that reside in their gut and how these interactions shape human health and disease.

Research suggests psilocybin may have effects therapeutic for depression. In this episode, we discuss some of the qualities of the psychedelic experience that most lend psilocybin to be potentially therapeutically beneficial for depression.

Dr. Bill Harris is one of the world's preeminent experts in the field of omega-3 fatty acid research. His work focuses on the roles that fatty acids play in cardiovascular and neurocognitive health.