Genetic variants that reduce brain-derived neurotrophic factor may increase risk of obesity due to reduced satiety

www.sciencedaily.com

From the article:

“The BDNF gene has previously been linked to obesity, and scientists have been working for several years to understand how changes in this particular gene may predispose people to obesity,” said Jack A. Yanovski, M.D., Ph.D.

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The BDNF protein plays several roles in the brain and nervous system and, at high levels, the protein can stimulate the feeling of fullness.