Common drug caused a 16% decrease in metabolic rate resulting in a 10% increase in weight gain by altering the composition of the gut microbiome.

This study was able to pinpoint the 10% increase in body mass to altered gut bacteria by transplanting the gut microbiome from mice given the risperidone drug to the control mice and the same effect occurred.

Risperidone is a common drug that is used to treat autism, bipolar disorder, and schizophrenia in adults and children and its prescribing rate has increased 8-fold in the last 2 decades.