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Seniors who consumed around 150g of cooked mushrooms weekly performed better on neuropsychological tests and had a 50% reduced risk of mild cognitive impairment compared to age-matched healthy controls.

This study was not a clinical trial so it is hard to establish causation but the researchers did see a dose-dependent effect with 75g of cooked mushrooms weekly also decreasing the risk of mild cognitive impairment.

One potential compound in mushrooms that may have brain benefits is ergothioneine. It is a unique antioxidant and anti-inflammatory compound that also accumulates in mitochondria. Humans are unable to synthesize ergothioneine on their own but it is present in a variety of mushrooms.

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    How does this compare to non-sedentary stimulus - like regular vigorous exercise? I.e. people who have daily 1 hour exercise regime can skip the mushrooms? Lot of people have sensitivity to mushrooms - so options good to know.

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      There is no way to replace the singular nourishments that a variety of mushrooms can offer. Research this on the internet…fungi are just beginning to be noticed and there are millions of them that have yet to be studied. They do come in capsules, as supplements as well, if you have a hard time digesting the mushrooms. Dr. Paul Stamets is the current authority on this subject.

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      Any kind of Mushrooms?

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        It says above that humans cannot synthesize ergothionine. This doesn’t seem correct because ergothonine is a phase in the glutamate cycle in the brain. However this may be let us keep on eating mushrooms esp. the King Oyster variety!

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          Would these findings apply to the various medicinal mushroom products from companies like Four Sigmatic, e.g., lions mane, chaga, cordyceps?