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      <h3 class="bold">
        [Podcast] Q&amp;A #81: Beta-Glucan vs. Psyllium—LDL Reduction, PFAS, &amp; Gluten
      </h3>
</a>    <p>
      Beta-glucan versus psyllium for lowering LDL, PFAS reduction, creatine and caffeine, urolithin A, exogenous ketones, IVF, Botox, and sauna.
...
          <span class="search-tag">rhonda</span>
          <span class="search-tag">pollution</span>
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          <span class="search-tag">creatine</span>
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          <span class="search-tag">Exogenous ketones </span>
          <span class="search-tag">cholesterol</span>
          <span class="search-tag">Ubiquinol</span>
          <span class="search-tag">PFAS</span>
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      <h3 class="bold">
        [Podcast] Aliquot #138: Why Sedation Isn&#39;t Sleep and What Actually Works
      </h3>
</a>    <p>
      Many of the substances people use to relax, sleep, or stay alert quietly reshape the biology of sleep...
...
          <span class="search-tag">aliquot</span>
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        [Topic] Urolithin A
      </h3>
</a>    <p>
      [toc]
Urolithin A is a postbiotic—a compound our gut microbes can form from ellagitannins and ellagic acid, polyphenols found in foods such as pomegranates, strawberries, and walnuts. 
Because production depends on the presence of specific gut microbes, people fall into distinct &quot;metabotypes&quot; (A = good UA producers, B = partial producers, 0 = non-producers), and only a minority make large amounts from diet alone. Therefore, purified UA supplements bypass that microbiome variability.[ref doi=&#39;10.3389/fmicb.2017.01521&#39;]
Mechanistically UA is best known as an inducer of mitophagy—the selective au...
          <span class="search-tag">immune system</span>
          <span class="search-tag">gut</span>
          <span class="search-tag">aging</span>
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          <span class="search-tag">microbiome</span>
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        [Podcast] How Magnesium Supports DNA Repair and Genomic Stability
      </h3>
</a>    <p>
      Dr. Rhonda Patrick explains how magnesium supports DNA repair and why low intake may contribute to accumulated cellular damage.
...
          <span class="search-tag">magnesium</span>
          <span class="search-tag">diet</span>
          <span class="search-tag">cancer</span>
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          <span class="search-tag">micronutrients</span>
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        [Topic] Zinc
      </h3>
</a>    <p>
      [toc position=&#39;left&#39;]
Background
Zinc is an essential nutrient that participates in numerous biological processes and modulates the activity of more than 300 enzymes and 2,000 transcription factors.[ref doi=&#39;10.1136/bmj.326.7386.409&#39;] First identified for its influence on growth and development, zinc is now understood to play critical roles in immune function, protein synthesis, wound healing, DNA synthesis, and cell division. 
History
The importance of zinc in the human diet first became apparent in the early 1960s, after a patient with a rare syndrome presented to Dr. Ananda Prasad, a physic...
          <span class="search-tag">nutrition</span>
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          <span class="search-tag">zinc</span>
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        [Podcast] Q&amp;A #2: Protein After 65, Saturated Fat &amp; Longevity—Plus Whole Grains
      </h3>
</a>    <p>
      Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&amp;amp;A session.
...
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        [Podcast] Gordon Lithgow, Ph.D. on Protein Aggregation, Iron Overload &amp; the Search for Longevity Compounds
      </h3>
</a>    <p>
      Dr. Gordon Lithgow discusses the roles of protein aggregation, iron overload, and others in the aging process.
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        [Podcast] Dr. Aubrey de Grey and Dr. Rhonda Patrick Talk Aging
      </h3>
</a>    <p>
      Dr. Aubrey de Grey discusses technologies that can repair the various types of damage that occur during the aging process.
...
          <span class="search-tag">aging</span>
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          <span class="search-tag">dna damage</span>
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        [Podcast] Do Antioxidants Cause Cancer?
      </h3>
</a>    <p>
      Dr. Rhonda Patrick explains what antioxidants are, why they are important, and how they prevent DNA damage, a well-known cancer initiator.
...
          <span class="search-tag">cancer</span>
          <span class="search-tag">rhonda</span>
          <span class="search-tag">selenium</span>
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      <h3 class="bold">
        [Podcast] Rebuttal to Anti-Vitamin Editorial: &quot;Enough is Enough&quot;
      </h3>
</a>    <p>
      We critically examine an Annals editorial reviewing three multivitamin studies, their shortcomings, and relevant mechanisms.
...
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          <span class="search-tag">nutrition</span>
          <span class="search-tag">diet</span>
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