[Story] A low-dose nutrient blend restored key social behaviors in mouse models of autism.
...onal tests, each nutrient was also given on its own. The blend combined three nutrients: zinc, L-serine, and a mix of the branched-chain amino acids (BCAAs) leucine, isoleucine, and valine. The nutrients improved several abnormalities in behavior and brain function: In mouse models of autism that r... autism supplements
Read more[Story] The amino acid leucine may act as a nutrient signal that enhances mitochondrial function and increases cellular energy capacity.
...est of the cell—and how this affects mitochondrial metabolism. In some experiments, leucine was compared with the related branched-chain amino acids (BCAAs) isoleucine and valine, or with a broader panel of essential amino acids. Leucine produced rapid, specific changes in mitochondrial function: ... mitochondria protein
Read more[Topic] Ultra-processed Foods (UPFs)
[toc position='left'] Ultra-processed foods (UPFs) have quietly taken over modern diets, making up nearly 60% of the average American's daily intake. Unlike whole or minimally processed foods, UPFs are industrial formulations packed with additives, artificial ingredients, and refined sugars and fats designed to enhance taste and shelf life—but at a significant cost to health. These foods don't just contribute to obesity and metabolic disorders; emerging research shows they actively rewire the brain, altering decision-making, impulse control, and reward processing in ways that drive overeating.... brain insulin resistance fatty liver nutrition obesity metabolism diabetes micronutrients insulin metabolic syndrome
Read more[Topic] Rapamycin
[toc position='left'] Consider a drug capable of reversing the effects of aging on the heart, restoring its youthful function. That's what researchers observed when they gave dogs rapamycin—a drug traditionally used to treat certain cancers and prevent organ transplant rejection. The findings were striking: The dogs exhibited marked improvements in heart function, effectively reversing the age-related changes typically seen in aging. While these findings are remarkable, they add to a growing body of research indicating that rapamycin might enhance healthspan and promote longevity in various sp... aging autophagy metabolism immune system cancer drug
Read more[Podcast] Aliquot #110: Why I don’t mix bananas and polyphenols — and other smoothie tips
Foods contain a vast array of nutrients, fiber, and bioactive compounds packaged up into a complex physical-chemical structure called... ... aliquot nutrition dairy polyphenol
Listen now[Podcast] Q&A #56: Ozempic for Weight Loss—Muscle Loss, Side Effects, & Weight Regain
Dr. Rhonda Patrick explores creatine, dairy's effect on polyphenols, eggs' health impact, and new weight loss drugs like Ozempic in her latest Q&A. ... rhonda vitamin d omega-3 fasting cold stress sauna protein polyphenol red light therapy Hair GLP-1
Watch now[Podcast] Q&A Mashup #3: Fasting
This episode of the aliquot features a collection of clips covering a range of topics related to fasting - both intermittent and prolonged. Specific topics ... ... aliquot parkinson's fasting autophagy caffeine resveratrol carbohydrates
Listen now[Podcast] Q&A #1: Fasting and Autophagy—Plus Pregnancy and Postpartum Supplements
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session. ... rhonda nutrition alzheimer's cancer gut fasting circadian rhythm pregnancy vaccine autophagy sulforaphane time-restricted eating breast milk supplements ketogenic diet
Watch now[Story] [TIMELINE] Joe Rogan Experience #502 with Dr. Rhonda Patrick
...ain in order to be converted into serotonin by tryptophan hydroxylase (https://en.wikipedia.org/wiki/Tryptophan_hydroxylase) (TPH2) but competes with BCAAs for transport into the brain, which are transported preferentially. 00:25:55 (http://youtu.be/DgSLkakMDfE?t=00h25m55s) - Tryptophan (http://en.wi... omega-3 depression insulin fatty liver vitamin a isothiocyanates antioxidant protein dairy blood sugar metabolic syndrome myrosinase
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