Six months of cycling classes produce changes in DNA methylation patterns of adipose tissue relevant for type 2 diabetes and obesity
From the article:
Using technology that analyses 480 000 positions throughout the genome, they could see that epigenetic changes had taken place in 7,000 genes (an individual has 20-25 000 genes). They then went on to look specifically at the methylation in genes linked to type 2 diabetes and obesity.
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“We found changes in those genes too, which suggests that altered DNA methylation as a result of physical activity could be one of the mechanisms of how these genes affect the risk of disease,” says Tina Rönn, adding that this has never before been studied in fat cells and that they now have a map of the DNA methylome in fat.