A standard American-like diet caused osteoarthritis in mice by changing the composition of the gut microbiome which was reversed by a prebiotic.
www.urmc.rochester.edu
Does microbiome composition drive osteoarthritis?
A standard American-like diet caused osteoarthritis in mice by changing the composition of the gut microbiome and subsequently increasing inflammation. The osteoarthritis was reversed by a prebiotic, called oligofructose.
Enjoying this research? Get deeper insights like this delivered every other week.
Every other week our Premium Members receive deep dives like this alongside Rhonda's commentary and 8+ other hand-picked papers.
Just reducing inflammation with the prebiotic was enough to protect joint cartilage from degeneration, supporting the idea that inflammation and not just biomechanical forces drive osteoarthritis and joint degeneration.