Episodes
Dr. Guido Kroemer describes how mitophagy contributes to the pathophysiology of neurodegenerative disease and how autophagy might mitigate these processes.
Dr. Guido Kroemer describes how fasting associated with sickness behavior is critical to surviving infection.
Dr. Guido Kroemer describes the complex relationship that exists between cancer cells, the immune system, and autophagy.
Dr. Guido Kroemer discusses changes that occur within cells that signal the need to induce autophagy.
Dr. Guido Kroemer describes the anti-diabetes and anti-obesity effects of exercise-induced autophagy.
Dr. Guido Kroemer describes the interplay between protein deacetylation and autophagy.
Dr. Guido Kroemer describes how intermittent fasting recapitulates the life-extension benefits of caloric restriction without some of the drawbacks.
Dr. Guido Kroemer discusses the autophagy-inducing qualities of coffee.
Dr. Guido Kroemer describes the autophagy-inducing behaviors he practices as part of his healthy lifestyle.
Dr. Guido Kroemer describes the autophagy-inducing effects of calorie restriction mimetics such as spermidine and resveratrol.
Dr. Guido Kroemer describes the spectacular biological phenomenon known as autophagy.
Dr. Guido Kroemer describes the current state of knowledge about the minimum amount of time required for fasting-induced autophagy in humans.
Dr. Satchin Panda describes the beneficial effects of time-restricted feeding in mice in terms of mitochondrial health.
Dr. Satchin Panda explains the role of the suprachiasmatic nucleus – the body's master clock – and how it affects metabolism.
Dr. Satchin Panda describes CLOCK's varied response to light and food and how those responses affect metabolism.
View our episode archive.