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@janine Yes! This paper is awesome! The tumerone was able to increase the neural stem cell population by 45%. That is robust and similar to what some neurotropic growth factors can do. I’m really excited about this data!
Does cooking (boiling) destroy the beneficial compounds found in turmeric?
I have not read any literature that curcumin or tumerone are heat-sensitive.
Then this makes supplementing with turmeric and piperine very easy, and delicious :) In fact, I used to do it unknowingly dozens of times before.
How well does this translate to oral turmeric intake?
In this study tumerone was injected to brain but other studies translate to 5-6 grams per day. However, this was administered without piperine, which increases bioavailability of curcumin (and likely tumerone) by 2000%. That would suggest that 300mg-1000mg may be a decent range but I’m looking for more studies to confirm.
Thank you for all your hard work!
Are there any studies showing bioavailbility of curcumin or turmerone and weather they pass the blood brain barrier?
Yes, they do pass the BBB.
Fats also increase the Bioavailibility such as olive oil
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