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    @janine Yes! This paper is awesome! The tumerone was able to increase the neural stem cell population by 45%. That is robust and similar to what some neurotropic growth factors can do. I’m really excited about this data!

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      Does cooking (boiling) destroy the beneficial compounds found in turmeric?

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        I have not read any literature that curcumin or tumerone are heat-sensitive.

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          Then this makes supplementing with turmeric and piperine very easy, and delicious :) In fact, I used to do it unknowingly dozens of times before.

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            mmmmm…curry…

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      How well does this translate to oral turmeric intake?

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        In this study tumerone was injected to brain but other studies translate to 5-6 grams per day. However, this was administered without piperine, which increases bioavailability of curcumin (and likely tumerone) by 2000%. That would suggest that 300mg-1000mg may be a decent range but I’m looking for more studies to confirm.

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          Thank you for all your hard work!

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            Are there any studies showing bioavailbility of curcumin or turmerone and weather they pass the blood brain barrier?

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              Yes, they do pass the BBB.

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                Fats also increase the Bioavailibility such as olive oil