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Hydroxycitrate is reputed to have negative effects on the liver. Have you found this is to be true?
The reason I ask is I was going to take it as a supplement and then read some negative stuff about it.
Second time watching this excellent discussion. Reminded me of a series I just watched in which Dr. Kroemer participated - Rethinking Cancer Paris 2017. Although most of this was not new (Seyfried & Longo for example, some was (presentation by Larent Schwartz who also discussed hydroxycitrate).
Thanks Rhonda for another amazing podcast.
This episode is particularly relevant to me as I’ve just been diagnosed with Stage IV colon cancer & I would really like to find out more information about the human equivalent levels for the CRM’s (Spermidine, and Hydroxycitric, and Resveratrol) used in the studies.
Looks like: daily administration of 900 mg/kg hydroxycitrate (HC) in drinking water; or 30 mg/kg SB204990 (SB), 25 mg/kg resveratrol (Resv), 10 mg/kg C646, 50 mg/kg spermidine (Spd), 5 mg/kg rapamycin (Rapa).
I will be visiting my oncologist tomorrow to discus my treatment / chemo plan, so would really appreciate any info you can share ASAP. Many thanks.
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