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Vitamin C, which has previously been shown in some studies to reduce inflammatory markers in conditions like rheumatoid arthritis, may improve emotional state of acutely hospitalized patients.

From the article:

Patients administered vitamin C had a rapid and statistically and clinically significant improvement in mood state, but no significant change in mood occurred with vitamin D, the researchers discovered. […] About one in five acute-care patients in our hospital have vitamin C levels so low as to be compatible with scurvy,“ added Hoffer.

Vitamin C, which concentrates in immune cells called neutrophils and lymphocytes at concentrations 50 to 100-times greater than plasma, play an important role in generating the so-called oxidative burst used by these cells to attack invading bacteria.

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