1. 3
  1. You must first login , or register before you can comment.

    Markdown formatting available

  2. 1

    This is an interesting study. I have been taking passionfruit leaves for some time in the evening as it helps sleep. I grow the vines in my yard. Any ideas on the g/kg dose implied by these studies?

    1. 1

      The only issue with aspirin is that it seems to cause intestinal permeability (despite buffering), any hacks to prevent that and still get the benefits?

      1. 4

        “It turns out that aspirin not only increases the function of mitochondria, it also increases the number of mitochondria. Using a staining method called MitoTracker Green dye, the researchers discovered that aspirin increased the total concentration of mitochondria by two to three times. Since the most notable hallmark of aging is decreased numbers of mitochondria with decreased mitochondrial function, this data makes aspirin look like the best anti-aging substance that has ever come along.

        So should we all run out and start taking aspirin every day? I think there is a better way. It turns out that within a matter of less than 15 minutes, the liver converts aspirin to another substance called salicylic acid. So the researchers reasoned that the effects of aspirin might be from salicylic acid instead of from aspirin itself. So to test for that, they repeated the same experiments using salicylic acid instead of aspirin. And guess what? The results were the same! The salicylic acid did just as well as the aspirin. And salicylic acid does not have the side effect baggage that aspirin has. So how can we take advantage of this new information? It’s quite easy.

        Willow bark is an herb that contains the substance salicin. And when we eat willow bark, our livers convert the salicin to salicylic acid. So by taking willow bark, it is possible to get the same mitochondrial-stimulating effects that come from aspirin.“ Dr. Frank Shallenberger

        Abbreviated name Botanical name Plant part used

        PE4 Cimicifuga racemosa Root and rhizome Black cohosh

        PE5 Valeriana officinalis L. Root Valerian

        PE6 Passiflora incarnate L. Whole plant passion flower

        PE8 Ginkgo biloba Leaf Ginkgo biloba

        PE12 Apium graveolens L. Seed wild celery

        PE21 Salix alba Bark white willow

        1. 1


        2. 2

          Looks like I found it, there’s 2 papers about this research:



          All sources are “Idunn Technologies”

          PE4, PE5, PE6, PE8, PE12 and PE21 slow yeast aging:
          Abbreviated name        Botanical name              Plant part used
           PE4                    Cimicifuga racemosa         Root and rhizome
           PE5                    Valeriana officinalis L.    Root    
           PE6                    Passiflora incarnate L.     Whole plant
           PE8                    Ginkgo biloba               Leaf        
           PE12                   Apium graveolens L.         Seed    
           PE21                   Salix alba                  Bark
          1. 1


          2. 2

            Rather useless article… From the website it seems the referenced research is still unpublished. The only published work this team seems to have so far is this:

            Longevity extension by phytochemicals. Leonov A, Arlia-Ciommo A, Piano A, Svistkova V, Lutchman V, Medkour Y, Titorenko VI. Molecules. 2015 Apr 13;20(4):6544-72. Review. http://www.ncbi.nlm.nih.gov/pubmed/25871373

            1. 2

              That’s all well and good, but what are the 6? (Willow bark is of course referring to the precursor of modern day aspirin.)