Exercise causes acute elevation of IL-6 which reduces postprandial blood glucose levels and insulin secretion by delaying gastric emptying in men with type 2 diabetes.
IL-6 is a cytokine with both negative and positive effects. Chronic elevation of IL-6 reflects ongoing inflammation and is linked to type 2 diabetes and atherosclerosis. In contrast, acute elevation of IL-6 from exercise inhibits inflammatory cytokines and stimulates the production of anti-inflammatory cytokines in humans.
To learn more about the role of exercise-induced IL-6, the postprandial inflammatory response and their effects on the brain…check out my interview with Dr. Charles Raison. This episode has a timeline, transcript, summary, and glossary to help find and understand the talking points.
Charles Raison, MD podcast: https://www.foundmyfitness.com/episodes/charles-raison