Mothers who supplemented with a high-dose probiotic during late pregnancy and while nursing lowered inflammatory biomarkers in breastmilk and improved symptoms of colic in their newborns.

This was a double-blind, randomized, placebo-controlled clinical trial. Mothers were given the probiotic visbiome (900 billion probiotics which equals 2 packets per day) at the start of the third trimester and continued until four weeks after delivery.