Adding a lysophospholipid form of EPA (LPC-EPA) to the diet can increase levels of EPA in the brain 100-fold in mice.
www.sciencedaily.com
From the article:
The amount of LPC-EPA in the diet required for this increase is rather small for mice – less than a milligram per day. The human equivalent would amount to less than a quarter of a gram per day. They report their results in the Journal of Lipid Research.
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He reports that providing EPA in the form of lysophospholipid, unlike the type present in fish oil supplements, escapes degradation by pancreatic enzymes which render it unable to pass into the brain.