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I’m not sure what this is supposed to prove. Firstly it’s a “fasting mimicking diet” in which the participants eat commercial preparations of carbs, protein and fat - i.e. not entirely dissimilar to SlimFast shakes.
Secondly they are on a pretty decent calorie deficit for 5 days a month which obviously causes them to lose weight. And we know that all those disease risk factors can be lowered by being on a diet and losing weight.
What we can’t know, from this, is whether the timing is doing anything special.
Lastly it appears to be be done on behalf of a company who make the supplement/food which, whilst that doesn’t negate it entirely, doesn’t offer the confidence of an impartial, independent trial.
Can you provide the full reference for Dr. Pandas article showing the 28% lower body mass and 70% lower fat mass with time restricted feeding please? Can you also confirm the duration of the experimental protocol (e.g. 4 weeks, 8 weeks, 12 weeks ect.) Great podcast by the way!
Here is the full reference for those data.The experimental protocol lasted 12 weeks. Hope this helps!
Oh….mice, not humans then?