Dr. Ben Bikman and Rhonda Patrick discuss the primary causes of insulin resistance and how to reverse it in as little as 90 days. ... insulin resistance insulin blood sugar diabetes saturated fat diet nutrition

[toc position='left'] Consider a drug capable of reversing the effects of aging on the heart, restoring its youthful function. That's what researchers observed when they gave dogs rapamycin—a drug traditionally used to treat certain cancers and prevent organ transplant rejection. The findings were striking: The dogs exhibited marked improvements in heart function, effectively reversing the age-related changes typically seen in aging. While these findings are remarkable, they add to a growing body of research indicating that rapamycin might enhance healthspan and promote longevity in various sp... aging autophagy metabolism immune system cancer drug

Graying hair is a cardinal sign of aging, typically beginning in a person’s fourth or fifth decade. Nutritional deficiencies, including low intake of protein, vitamin B12, iron, and copper, can contribute to premature graying. However, a recent review found that some medications may promote gray hair re-pigmentation. Researchers reviewed 27 studies and case reports of medication-induced gray hair re-pigmentation, totaling 133 patients. They categorized the various drugs as anti-inflammatories, stimulators of melanogenesis (the production of melanin, the pigment responsible for hair, skin, and... nutrition aging inflammation drug Hair

Antibodies that destroy myelin in multiple sclerosis may cross-react with casein, a milk protein. Multiple sclerosis (MS) is a neurodegenerative and autoimmune disease caused when the immune system attacks myelin proteins on nerves, mistaking them for proteins produced by pathogens. The cause of this immune confusion is complex but may involve exposure to proteins found in cow's milk, which anecdotally worsen MS symptoms for some patients. New research supports this anecdotal evidence, finding that MS autoantibodies cross-react with casein, the principal protein in cow's milk. In order to crea... brain multiple sclerosis autoimmunity

[toc position='left'] Butyrate (from the Ancient Greek word for "butter") is a short-chain fatty acid (SCFA) that occurs naturally in butter and other foods and is also produced by microbes in the gut. Microbial production of short-chain fatty acids, including acetate and propionate, occurs in the colon during the fermentation of indigestible fibers found in plant foods such as legumes, fruits, nuts, cereals, and whole grains. In the gut, butyrate is the preferred fuel source for colonocytes, the skin-like cells that line the colon.[ref pmid='21978911'] Butyrate participates in a wide array of... exercise fasting butyrate gut microbiome ketosis immune system intestinal permeability

[toc position='left'] Introduction Vitamin D is a fat-soluble vitamin that is stored in the liver and fatty tissues of the body. Perhaps best known for its role in maintaining calcium balance and bone health, vitamin D is critical in many physiological processes, such as blood pressure regulation, immune function, and cell growth. Poor vitamin D status is implicated in the pathogenesis of many acute and chronic diseases, including rickets, osteoporosis, multiple sclerosis, and cancer. Vitamin D is a controversial topic in the scientific community and has contributed to much debate regarding t... gut blood pressure vitamin d aging vitamin k calcium

Irritable bowel syndrome (IBS), an intestinal disorder characterized by abdominal pain, bloating, and alternating episodes of diarrhea and constipation, affects as many as 14 percent of people living in the United States. Evidence suggests that people with IBS often have dysbiosis, an imbalance in the microbial makeup of the gut. A recent study indicates that human milk oligosaccharides may be beneficial in modulating the gut microbial profile of people who have IBS. Human milk oligosaccharides (HMOs) are complex, indigestible sugars in breast milk. They serve as prebiotics – compounds that i... gut

COVID-19 Q&A Series Part 1: Rhonda Patrick, Ph.D. addresses subscriber questions in this multi-part series. ... covid-19 vitamin d vitamin c virus melatonin sauna autoimmunity

[toc position='left'] Nutrition in the first year of life is crucial to an infant's development and lifelong health. Early nutritional deficits are intrinsically linked to impaired mental and physical growth. Consequently, the risk of developing metabolic and cardiovascular diseases such as obesity, diabetes, and hypertension in childhood and later life is likely determined by early feeding and nutritional status. Breastfeeding is the biologically superior way to feed an infant. The American Academy of Pediatrics recommends exclusive breastfeeding for the first six months of an infant's life ... cancer breast cancer circadian rhythm nutrition brain microbiome heart disease diabetes inflammation alcohol stem cells immune system development intelligence