Exercising restores sensitivity of neurons that make one feel full via myokine signaling involving IL-6 and IL-10
www.sciencedaily.com
From the article:
“In obese animals, exercise increased IL-6 and IL-10 protein levels in the hypothalamus, and these molecules were crucial for increasing the sensitivity of the most important hormones, insulin and leptin, which control appetite,” Carvalheira explained.