Having just 8 to 12 drinks per week associated with shrinkage of the hippocampus in moderate drinkers.

www.scientificamerican.com

FTA:

The researchers found that moderate drinking over those 30-plus years was associated with degeneration and shrinking of the hippocampus, a region of the brain involved in memory and navigation, as well degeneration of the brain’s white matter.

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In essence, “the more people drank, the smaller their hippocampus,” said first author Anya Topiwala, a psychiatry professor at University of Oxford.