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Omega-3 supplementation in healthy humans increases several species of beneficial gut bacteria that produce short-chain fatty acids (double-blinded, randomized controlled trial).
Supplementation with omega-3 PUFAs was associated with increased abundance of butyrate-producing ‘beneficial’, bacterial genera such as Bifidobacterium, Lachnospira, Roseburia, and Lactobacillus.
An increase in SCFA-producing bacteria such as Bifidobacterium has been shown to reduce mucosal inflammatory tone in the gut.