Default mode network is suppressed by meditation practice | Roland Griffiths

Parent Episode: Roland Griffiths, Ph.D. on Psilocybin, Psychedelic Therapies & Mystical Experiences

Activity in the default mode network (DMN), a group of interacting brain regions implicated in self-related thinking, rumination, and depression, is suppressed by psilocybin and other psychedelic substances. Interestingly, strong evidence indicates that meditation also reduces DMN activity, likely due to its emphasis on the present and non-self-related thoughts. Teasing out the mechanisms by which psychedelics and meditation elicit their beneficial effects on the brain has proven challenging, however. In this clip, Dr. Roland Griffiths discusses similarities in the effects of psilocybin and meditation on the brain and their potential usefulness in treating depression.

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