Herpes virus and other pathogens relationship with Alzheimer's disease | Dale Bredesen

Parent Episode: Dr. Dale Bredesen on Preventing and Reversing Alzheimer's Disease

Alzheimer’s disease is a complex, multifaceted condition that manifests as three primary subtypes, one of which is inflammation-related. Exposure to pathogens, including certain oral bacteria, fungi, and members of the herpes virus family, promotes inflammation and upregulates the production of amyloid-beta protein in the brain. Interestingly, most people harbor latent herpes virus infections, and some evidence suggests that reactivation of the latent virus in the brain, particularly in APOE4 carriers, might increase the risk of developing Alzheimer’s disease. In this clip, Dr. Dale Bredesen describes the links between pathogen exposure and Alzheimer's disease.

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