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“Taking it a step further, they investigated how sodium and potassium impact blood pressure in men and women differently—a critical question since cardiovascular diseases disproportionately affect men compared to women due to differences in nitric oxide bioavailability, inflammation, electrolyte balance, and sympathetic nervous system activity.”
Small vessel disease is a generic term that describes dysfunction of blood vessels that occurs with aging and contributes to cognitive decline, cardiovascular disease, frailty, and stroke.
“After taking into account other factors, including age, race/ethnicity, poverty/income, tobacco and alcohol consumption, and physical activity, the authors also found that participants with overweight and obesity were nearly four times more likely to have low serum testosterone compared to lean males, independent of SSB consumption.”
“UPFs cause metabolic and cognitive changes in less than a week "...just 5 days of a high-calorie diet made the brains of these healthy, normal weight men structurally and functionally similar to people with obesity, and even after cutting the high-calorie foods out of their diet, these changes persisted for at least one week."”