Related Episodes for What time of day do we have peak cognitive performance? | Dr. Satchin Panda

“In a placebo-controlled study of eight healthy adults, adrenaline infusion lowered plasma magnesium, and levels had not recovered one hour later. Investigators proposed a shift into cells after beta-adrenergic stimulation; the study did not measure cortisol, urinary loss, total-body depletion, or clinical deficiency.”

“Based on findings from more recent studies using stable isotopes, which more accurately assess muscle protein anabolism and catabolism, Dr. Phillips believes that eating 1.2 to 1.6 grams of protein per kilogram of bodyweight (about 0.5 to 0.7 grams per pound) is likely optimal for muscle protein synthesis, especially as one ages.”

“Human trials suggest that alpha-lipoic acid can modestly improve selected lipid measures. A dose-response meta-analysis of 12 studies found reductions in total cholesterol, LDL cholesterol, and triglycerides across doses from 300 to 1,200 milligrams per day.”

“In contrast, a five-week trial in 181 people with diabetic polyneuropathy found that oral alpha-lipoic acid improved symptom scores, with more nausea, vomiting, and vertigo at higher doses. PQQ has a much smaller human evidence base.”